在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SERTAD1 Antibody, Biotin conjugated

  • 中文名稱:
    SERTAD1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA883406LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SERTAD1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SERTAD1
  • 別名:
    CDK4 binding protein p34SEI antibody; CDK4 binding protein p34SEI1 antibody; CDK4-binding protein p34SEI1 antibody; SEI-1 antibody; SEI1 antibody; SERTA domain containing 1 antibody; SERTA domain-containing protein 1 antibody; SERTAD1 antibody; SRTD1_HUMAN antibody; Transcriptional regulator interacting with the PHD-bromodomain 1 antibody; TRIP Br1 antibody; TRIP-Br1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human SERTA domain-containing protein 1 protein (1-236AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
  • 基因功能參考文獻(xiàn):
    1. Here, the authors show that transcriptional regulator interacting with the PHD-bromodomain 1 (TRIP-Br1, Sertad1), a newly identified protein with poorly characterized functions, acts as an adaptor that bridges the interaction of multiple Adenylyl cyclase isoforms with X-linked inhibitor of apoptosis protein (XIAP), a RING-domain E3 ubiquitin ligase. PMID: 28656888
    2. NEDD4-1 recognizes SERTA domain containing proline rich region of p34SEI-1. Residues of NEDD4-1 responsible for direct interaction with p34SEI-1 are identified by NMR titration experiments. PMID: 28666866
    3. SEI1 up-regulation induces genomic instability by inhibiting DNA damage response in ovarian cancer cells. PMID: 27697611
    4. Findings provide evidence that TRIP-Br1 functions as an oncogenic protein by providing cancer cells resistance to the hypoxia-induced cell death of breast cancer cells. PMID: 27035851
    5. TRIP-Br1 confers resistance to serum starvation-induced cell deaths by stabilizing the XIAP protein and inhibiting cellular ROS production. PMID: 26334958
    6. Data demonstrate that p34SEI-1 induces the activation of either AKT or ILK signaling on HER2/neu expression status. PMID: 24789658
    7. High SERTAD1 expression is associated with breast cancer. PMID: 23970032
    8. These results suggest that p34 (SEI-1) inhibits ROS-induced cell death through by indirectly inducing ubiquitination of ASK1. PMID: 21725208
    9. study shows that the p34SE1-1 expression level was not changed after H2O2 treatment at either protein or transcriptional levels PMID: 21344158
    10. Translocation of small amount of NM23H1 into the nucleus induced by the overexpressions of SEI1/SET could increase the frequency of sister chromatid exchangein esophageal cancers. PMID: 20570897
    11. p34SEI-1 strongly suppressed CREB-mediated transcription, and this suppression was overcome by excess amount of CBP PMID: 12736710
    12. interacts with low- and high-risk HPV11 and HPV16 E6 proteins in yeast, in vitro and in mammalian cell cultures PMID: 14675634
    13. p34SEI1 fragment 30-160 can bind, activate, and inhibit cyclin-dependent kinase CDK4; fragment 30-132 binds and activates but does not inhibit CDK4, while fragment 30-88 cannot bind, activate, or inhibit but retains LexA-mediated transactivation activity. PMID: 15065884
    14. p34(SEI-1) and p16(INK4A) have different roles in development of squamous cell carcinoma of the head and neck PMID: 16201750

    顯示更多

    收起更多

  • 數(shù)據(jù)庫鏈接:

    HGNC: 17932

    OMIM: 617850

    KEGG: hsa:29950

    STRING: 9606.ENSP00000350633

    UniGene: Hs.269898



主站蜘蛛池模板: 精品久久亚洲中文无码| 777米奇影院狠狠色| 2022国产日产欧产精品| 日韩激情无码不卡码| 小嫩妇好紧好爽再快视频| 日本午夜精品一区二区三区电影| 老男人久久青草av高清| 国产精品久久久久aaaa| 亚洲 成人 无码 在线观看| 欧美老妇牲交videos| 国产成人毛片在线视频软件| 久久婷婷五月综合色奶水99啪| 亚洲中文字幕无码永久在线不卡| 午夜福利理论片在线观看播放| 亚洲欧美精品suv| 男人天堂2018亚洲男人天堂| 国内精品自线一区二区三区2021| 中文字幕乱码免费| 国产精品无码人妻一区二区在线| 在线看片免费人成视频福利| 久久国产精品2020免费| 久久久久久久久888| 亚洲精品国产精品国自产观看| 亚洲真人无码永久在线| 99热这里只有精品国产免费免费 | 国产精品国产三级国产剧情| 99久re热视频这里只有精品6 | 潮喷大喷水系列无码| 欧美成人精品三级网站| 亚洲337少妇裸体艺术| 亚洲国产超清无码专区| 日韩无套无码精品| 少妇邻居内射在线| 精品国产一区二区三区四区精华液| 内射视频←www夜| 国产日韩在线视看第一页| 久久精品中文字幕无码| 亚洲精品国产综合久久一线| 污污污污污污污网站污| 麻豆高清免费国产一区| 在线综合亚洲欧洲综合网站|