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SERINC3 Antibody

  • 中文名稱:
    SERINC3兔多克隆抗體
  • 貨號:
    CSB-PA984539
  • 規格:
    ¥2024
  • 圖片:
    • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.
    • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/40.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SERINC3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SERINC3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide corresponding to a region derived from internal residues of Human serine incorporator 3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm.
  • 基因功能參考文獻:
    1. SERINC3 and SERINC5 together restricted HIV-1 replication, and this restriction was evaded by Nef PMID: 26416733
    2. TDE1 inhibits apoptosis and stimulates tumorigenesis PMID: 16547497
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region.
  • 蛋白家族:
    TDE1 family
  • 組織特異性:
    Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
  • 數據庫鏈接:

    HGNC: 11699

    OMIM: 607165

    KEGG: hsa:10955

    STRING: 9606.ENSP00000255175

    UniGene: Hs.272168



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