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SEPT1 Antibody

  • 中文名稱：
    SEPT1兔多克隆抗體
  • 貨號：
    CSB-PA004067
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using Septin 1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SEPT1
  • 別名：
    DIFF6 antibody; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase) antibody; LARP antibody; MGC20394 antibody; Peanut like protein 3 antibody; Peanut-like protein 3 antibody; PNUTL3 antibody; SEP1 antibody; SEPT1 antibody; SEPT1_HUMAN antibody; Septin 1 antibody; Septin-1 antibody; Serologically defined breast cancer antigen NY BR 24 antibody; Serologically defined breast cancer antigen NY-BR-24 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Septin 1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
  • 基因功能參考文獻：
    1. The SEPT1 may participate in cell-cell and/or cell-substrate interaction in DJM-1 and exert its function in a coordinated manner with other septins. PMID: 23087102
    2. Aurora-B binds and phosphorylates Septin1. PMID: 16179162
    3. An increase in Sept1 expression in all oral squamous-cell carcinoma-derived cell lines compared to human normal oral keratinocytes and oral premalignant lesions suggest that Sept1 expression could contribute to cancer progression, proliferation, or both. PMID: 17912427
  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 組織特異性：
    Expressed at high levels in lymphoid and hematopoietic tissues.
  • 數據庫鏈接：

    HGNC: 2879

    OMIM: 612897

    KEGG: hsa:1731

    STRING: 9606.ENSP00000460441

    UniGene: Hs.632176



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