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  4. SEMA6B Antibody

SEMA6B Antibody

  • 中文名稱：
    SEMA6B兔多克隆抗體
  • 貨號：
    CSB-PA862010LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA862010LA01HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA862010LA01HU at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SEMA6B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SEMA6B
  • 別名：
    SEM-SEMA-Y antibody; SEM6B_HUMAN antibody; sema domain; transmembrane domain (TM); and cytoplasmic domain; (semaphorin) 6B antibody; Sema Z antibody; SEMA-VIB antibody; Sema6b antibody; SEMAN antibody; semaphorin VIB antibody; Semaphorin-6B antibody; semaphorin-6Ba antibody; Semaphorin-Z antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Semaphorin-6B protein (756-888AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SEMA6B Antibody (CSB-PA862010LA01HU)，的標記方式是Non-conjugated。對于SEMA6B Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA862010LB01HU SEMA6B Antibody, HRP conjugated ELISA
    FITC CSB-PA862010LC01HU SEMA6B Antibody, FITC conjugated
    Biotin CSB-PA862010LD01HU SEMA6B Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons.; (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium.
  • 基因功能參考文獻：
    1. Semaphorin 6B is related to tumour differentiation and metastasis in vivo, and tumour cell migration, adhesion and invasion in vitro. PMID: 23781008
    2. states a clear relation among breast cancer and SEMA6B expression; moreover we describe for the first time the SEMA6Ba protein and report here the analysis of SEMA6Ba RNA messenger, the protein expression and the cellular localization PMID: 23665584
    3. Gene SEMA6B is strongly down regulated by peroxisome proliferator-activated receptors. PMID: 15177567
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Semaphorin family
  • 組織特異性：
    Expressed in the brain in GABAergic neurons.
  • 數據庫鏈接：

    HGNC: 10739

    OMIM: 608873

    KEGG: hsa:10501

    STRING: 9606.ENSP00000301293

    UniGene: Hs.465642



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