在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SEC31A Antibody, FITC conjugated

  • 中文名稱:
    SEC31A兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA020954LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SEC31A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    SEC31A antibody; KIAA0905 antibody; SEC31L1 antibody; HSPC275 antibody; HSPC334 antibody; Protein transport protein Sec31A antibody; ABP125 antibody; ABP130 antibody; SEC31-like protein 1 antibody; SEC31-related protein A antibody; Web1-like protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein transport protein Sec31A protein (335-503AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
  • 基因功能參考文獻:
    1. USP8 deubiquitinates Sec31A and inhibits the formation of large COPII carriers, thereby suppressing collagen IV secretion. PMID: 29604273
    2. findings suggest that AnxA11 maintains architectural and functional features of the ERES by coordinating with ALG-2 to stabilize Sec31A at the ERES. PMID: 25540196
    3. These results suggest that Sec31 phosphorylation by CK2 controls the duration of COPII vesicle formation, which regulates ER-to-Golgi trafficking. PMID: 23349870
    4. efficient COPII-dependent secretion, notably assembly of Sec13-Sec31, is required to drive epithelial morphogenesis in both two- and three-dimensional cultures PMID: 22331354
    5. SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas. PMID: 21109691
    6. t(4;9)(q21;p24) leads to a novel SEC31A-JAK2 fusion in Hodgkin lymphoma PMID: 21325169
    7. Genomic PCR and subsequent sequencing showed that the breakpoints were located in intron 23 of SEC31L1 and intron 20 of anaplastic lymphoma kinase PMID: 16161041
    8. three-dimensional reconstruction of Sec13/31 cages at 30 A resolution using cryo-electron microscopy and single particle analysis PMID: 16407955
    9. In vitro GST pull down analysis demonstrated that ALG-2 and its alternatively spliced isoform interact with the COPII component Sec31A in a Ca2+-dependent manner, and a biotin-labeled ALG-2 overlay assay revealed direct binding of ALG-2 to Sec31A. PMID: 17196169
    10. The Sec31 active fragment is accommodated in a binding groove supported in part by Sec23 residue Phe380. PMID: 17981133

    顯示更多

    收起更多

  • 相關疾病:
    A chromosomal aberration involving SEC31A is associated with inflammatory myofibroblastic tumors (IMTs). Translocation t(2;4)(p23;q21) with ALK.
  • 亞細胞定位:
    Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein. Cytoplasm, cytosol.
  • 蛋白家族:
    WD repeat SEC31 family
  • 組織特異性:
    Abundantly and ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 17052

    OMIM: 610257

    KEGG: hsa:22872

    STRING: 9606.ENSP00000347329

    UniGene: Hs.370024



主站蜘蛛池模板: 性做久久久久久免费观看| 任我撸在线视频| 久久精品国产99久久久古代| 乱亲女h秽乱长久久久| 火箭视频在线观看精品| 秋霞鲁丝片av无码| 2020年国产精品| 美女裸免费观看网站| 99偷拍视频精品一区二区| 亚洲中文字幕无码久久2017| 成人免费的视频| 3p人妻少妇对白精彩视频| 野花在线无码视频在线播放| 2018av无码视频在线播放| 日本va在线视频播放| 熟妇与小伙子matur老熟妇e| 精品国内自产拍在线观看视频| 国产美女爽到喷出水来视频| 精品性影院一区二区三区内射 | 久久日本片精品aaaaa国产| 麻豆一区二区在我观看| 在线天堂中文在线资源网| 国产在线 | 欧洲| 国产sm鞭打折磨调教视频| 99精品全国免费观看视频| 大伊香蕉精品一区视频在线 | 久久69精品久久久久久hb| 最新 国产 精品 精品 视频| 巨胸爆乳美女露双奶头挤奶| 1000部精品久久久久久久久| 亚洲色婷婷婷婷五月基地| 日本亚欧热亚洲乱色视频| 国产精品天干天干| 大肉大捧一进一出好爽mba| 亚洲一区无码中文字幕乱码 | 国产亚洲综合网曝门系列| 亚洲一区二区三区高清在线看| 久久国产精品久久久久久| 国产98色在线 | 国产| 又色又爽又黄的吃奶视频免费观看| 18禁止午夜福利体验区|