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  4. SEC23IP Antibody

SEC23IP Antibody

  • 中文名稱：
    SEC23IP兔多克隆抗體
  • 貨號：
    CSB-PA020949GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SEC23IP
  • 別名：
    MSTP053 antibody; p125 antibody; P125A antibody; Phospholipase antibody; S23IP_HUMAN antibody; Sec23 interacting protein p125 antibody; SEC23-interacting protein antibody; SEC23IP antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SEC23IP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
  • 基因功能參考文獻：
    1. A basic cluster and a hydrophobic interface in the DDHD and SAM domains, respectively, are required for p125A-mediated functional endoplasmic reticulum exit site assembly. PMID: 24522181
    2. Xenopus sec23ip is required for normal neural crest cell development, suggesting a role for the human ortholog in Waardenburg syndrome neural crest defects. PMID: 20308572
    3. The results suggest that p125A is part of the Sec13/Sec31A subcomplex and facilitates ER export in mammalian cells. PMID: 20679433
    4. p125 is a mammalian-specific component of ER exit sites and participates in the organization of this compartment PMID: 15623529
  • 亞細胞定位：
    Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.
  • 蛋白家族：
    PA-PLA1 family
  • 組織特異性：
    Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17018

    OMIM: 617852

    KEGG: hsa:11196

    STRING: 9606.ENSP00000358071

    UniGene: Hs.435004



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