在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SCUBE3 Antibody

  • 中文名稱:
    SCUBE3兔多克隆抗體
  • 貨號:
    CSB-PA020868GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SCUBE3
  • 別名:
    CEGF3 antibody; CUB and EGF containing protein 3 antibody; CUB and EGF-like domain-containing protein 3 antibody; CUB domain and EGF like repeat containing 3 antibody; DKFZp686B09105 antibody; DKFZp686B1223 antibody; DKFZp686D20108 antibody; FLJ34743 antibody; OTTHUMP00000016250 antibody; SCUB3_HUMAN antibody; SCUBE 3 antibody; SCUBE3 antibody; Signal peptide antibody; Signal peptide CUB and EGF like domain containing protein 3 antibody; Signal peptide CUB domain EGF like 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SCUBE3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
  • 基因功能參考文獻:
    1. The results of this pioneering study indicate that SCUBE protein family appears to have a probable role in the pathogenesis and angiogenesis development in psoriasis and SCUBE 1 and 3 may be novel markers of angiogenesis in psoriasis. PMID: 28238185
    2. Elevated expression of SCUBE3 in osteosarcoma tissues correlated with poor prognosis of the osteosarcoma patients. PMID: 27259322
    3. Results indicated that SCUBE3 might be involved in regulating the epithelial-mesenchymal transition (EMT) and malignant progression in NSCLC. PMID: 24390364
    4. Scube3 facilitates both TGFbeta and Hh signalling within an overall role of facillating inflammatory angiogenesis. PMID: 24084593
    5. results show that SCUBE3 knockdown was associated with lower vascular permeability in the tumor and effectively inhibited the metastatic potential of non-small-cell lung carcinoma PMID: 23420440
    6. in lung cancer cells, SCUBE3 could serve as an endogenous autocrine and paracrine ligand of TGF-beta type II receptor, which could regulate TGF-beta receptor signaling and modulate EMT and cancer progression PMID: 21441952
    7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20546612
    8. may act locally and/or distantly through a proteolytic mechanism, and may play an important role in bone cell biology PMID: 15234972

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted. Cell surface.
  • 組織特異性:
    Highly expressed in osteoblasts. In normal lung, mainly expressed in bronchial epithelial cells. Tends to be up-regulated in lung cancer cells.
  • 數據庫鏈接:

    HGNC: 13655

    OMIM: 614708

    KEGG: hsa:222663

    STRING: 9606.ENSP00000274938

    UniGene: Hs.12923



主站蜘蛛池模板: 国产成人拍精品视频午夜网站| 久久精品国产色蜜蜜麻豆| 国产成人无码性教育视频| 色婷婷av一区二区三区之红樱桃| 大香伊蕉在人线国产网站首页 | 少妇裸交aa大片| 久久久久久久99精品免费观看| 天天爽夜夜爽人人爽一区二区| 久久天天躁狠狠躁夜夜av| 国产亚洲精品aaaaaaa片 | 爆乳护士一区二区三区在线播放| 最新无码a∨在线观看| 日韩精品无码熟人妻视频| 亚洲丰满熟女一区二区v| 国产亚洲精品久久久网站好莱| 国产精品久久久久久久久久久久午衣片 | 日本狂喷奶水在线播放212| 亚洲国产成人超a在线播放| 精产国品一二三产品麻豆| 国产精品9999久久久久| 国产佗精品一区二区三区| 少妇邻居内射在线| 亚洲香蕉视频天天爽| 免费女上男下xx00xx00视频| 久久久肥妇熟女ⅹxxx毛片| 无码精品人妻一区二区三区湄公河| 欧美性猛交xxxx乱大交3| 色先锋av资源中文字幕| 无码人妻视频一区二区三区| 综合无码成人aⅴ视频在线观看 | 欧美日本日韩aⅴ在线视频| av无码欧洲亚洲电影网| 亚洲精品一区二区三区在线| 中文字幕精品久久久久人妻红杏ⅰ | 精品久久久久久综合日本| 老司机久久99久久精品播放免费| 99久e在线精品视频在线| 99国产精品久久久久久久久久久| 综合网日日天干夜夜久久| аⅴ天堂中文在线网官网| 国产成人乱色伦区|