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SCOC Antibody

  • 中文名稱：
    SCOC兔多克隆抗體
  • 貨號：
    CSB-PA020854LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA020854LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA020854LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA020854LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SCOC Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SCOC
  • 別名：
    HRIHFB2072 antibody; Scoc antibody; SCOC_HUMAN antibody; SCOCO antibody; Short coiled coil protein antibody; Short coiled-coil protein antibody; UNC-69 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Short coiled-coil protein (1-121AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SCOC Antibody (CSB-PA020854LA01HU)，的標記方式是Non-conjugated。對于SCOC Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA020854LB01HU SCOC Antibody, HRP conjugated ELISA
    FITC CSB-PA020854LC01HU SCOC Antibody, FITC conjugated
    Biotin CSB-PA020854LD01HU SCOC Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Positive regulator of amino acid starvation-induced autophagy.
  • 基因功能參考文獻：
    1. SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis] PMID: 27023175
    2. SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction. PMID: 24098481
    3. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process. PMID: 24116125
    4. The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037
  • 亞細胞定位：
    Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
  • 蛋白家族：
    SCOC family
  • 組織特異性：
    Widely expressed with highest levels in brain, heart and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 20335

    KEGG: hsa:60592

    STRING: 9606.ENSP00000377751

    UniGene: Hs.480815



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