在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SCNN1D Antibody

SCNN1D Antibody

  • 中文名稱：
    SCNN1D兔多克隆抗體
  • 貨號：
    CSB-PA040298
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SCNN1D
  • 別名：
    Amiloride sensitive sodium channel subunit delta antibody; Amiloride-sensitive sodium channel subunit delta antibody; Delta ENaC antibody; Delta NaCH antibody; Delta-ENaC antibody; Delta-NaCH antibody; DNACH antibody; ENaC Delta antibody; ENaCD antibody; ENaCdelta antibody; Epithelial Na(+) channel subunit delta antibody; MGC149710 antibody; MGC149711 antibody; Nonvoltage gated sodium channel 1 subunit delta antibody; Nonvoltage-gated sodium channel 1 subunit delta antibody; SCNED antibody; SCNN1D antibody; SCNND_HUMAN antibody; Sodium channel, nonvoltage gated 1, delta antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ENaCδ.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
  • 基因功能參考文獻：
    1. delta-ENaC expression is low in NCI-H441, Calu-3, and ATI cells and does not contribute to transepithelial sodium absorption PMID: 25677639
    2. study characterized a new variant, delta2 ENaC, in lung epithelial cells; heterologous delta2betagamma ENaC exhibited a number of divergent features from the delta1betagamma counterpart in biophysics and pharmacology, regulation, and the lifespan of proteins PMID: 22505667
    3. delta-ENaC undergoes dynamin-independent endocytosis as opposed to alphabetagamma-channels. PMID: 22159085
    4. These results suggest that COMMD1 downregulates deltaENaC activity by reducing deltaENaC surface expression through promoting internalization of surface deltaENaC to an intracellular recycling pool, possibly via enhanced ubiquitination. PMID: 21741370
    5. Cpt-cAMP activates human epithelial sodium channels via relieving self-inhibition. PMID: 21419751
    6. CPT-cGMP Stimulates Human Alveolar Fluid Clearance by Releasing External Na+ Self-Inhibition of ENaC. PMID: 21562313
    7. Data support a physiological role for SGK1.1 in the regulation of delta-ENaC through a pathway that differs from the classical one and suggest that the kinase could serve as an integrator of different signaling pathways converging on the channel. PMID: 20631247
    8. delta ENaC is regulated by Murr1 PMID: 14645214
    9. ENaCdelta activity is regulated by protons, and may contribute to the pH sensation and/or pH regulation in the human brain PMID: 14726523
    10. ENaCdelta is chemically activated by capsazepine by a proton-dependent mechanism PMID: 15308635
    11. analysis of anovel spliced variant of the ENaC delta-subunit in the human brain PMID: 16930535
    12. ENaC delta isoforms are widely expressed in pyramidal cells of the human and monkey cerebral cortex and in different neuronal populations of telencephalic subcortical nuclei. PMID: 17472699
    13. Expression analyses at the level of mRNA clearly revealed that ENaC delta transcript was strongly expressed in human melanoma cells using reverse transcription-polymerase chain reaction and cell-based in situ hybridization techniques. PMID: 18073141
    14. ENaCdelta is a candidate molecule for pH sensing in the gastrointestinal system in humans, providing a novel therapeutic target for gastro-oesophageal reflux disease PMID: 18951889
    15. the delta-subunit of ENaC alters proteolytic channel activation and enhances base-line channel activity PMID: 19717556
    16. delta ENaC is a proton sensor PMID: 15084585

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1D subfamily
  • 數據庫鏈接：

    HGNC: 10601

    OMIM: 601328

    KEGG: hsa:6339

    STRING: 9606.ENSP00000368411

    UniGene: Hs.512681



主站蜘蛛池模板： 西西艺术人像摄影| 奇米影视777四色米奇影院| 久久国产精品成人片免费| 一本大道久久香蕉成人网| 黑人大战欲求不满人妻| 极品新婚夜少妇真紧| 蜜芽久久人人超碰爱香蕉| 无码av片av片av无码| 国产精品久久久久久tv| 精品久久久久香蕉网| 国产成人久久av免费高潮| 国产精品色无码av在线观看| 国产精品自在线一区| 午夜爽爽爽男女免费观看影院| 天天爽夜夜爽人人爽曰| 日韩欧美亚洲综合久久| 乱人伦xxxx国语对白| 亚洲乱码日产精品bd在线| 日产精品一二三区| 国产精品久久久久久久久免费| 久久99国产精品成人| 人人人爽人人爽人人av| ww欧日韩视频高清在线| 丰满熟妇人妻av无码区| r级无码视频在线观看| 中文字幕久久综合伊人| 不卡无码人妻一区二区三区| 国产精品无码无卡在线播放| 欧美孕妇变态重口另类| 秋霞av在线露丝片av无码| 亚洲精品无码永久中文字幕| 国产人碰人摸人爱免费视频| 色欲av无码一区二区人妻| 欧美综合精品久久久久成人影院| 亚洲成 人 综合 亚洲欧洲| 成人午夜精品无码区久久| 国产剧情麻豆女教师在线观看| 纯肉无遮挡无码日本动漫| 中文无码av在线亚洲电影| 亚洲老妇色熟女老太| 日日拍夜夜嗷嗷叫|日日摸|