在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SCN2B Antibody

SCN2B Antibody

  • 中文名稱：
    SCN2B兔多克隆抗體
  • 貨號：
    CSB-PA020838ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA020838ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SCN2B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SCN2B
  • 別名：
    SCN2B; UNQ326/PRO386; Sodium channel subunit beta-2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sodium channel subunit beta-2 protein (30-160AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
  • 基因功能參考文獻：
    1. Findings add to the understanding of beta2 role in Nav 1.5 trafficking and localisation, which must influence cell excitability and electrical coupling in the heart. PMID: 28597987
    2. The authors identified a flexible loop formed by (72)Cys and (75)Cys, a unique feature among the four beta-subunit isoforms. PMID: 26894959
    3. With increased beta-2 expression, prostate cancer cells display a trend of enhanced association with nerve axons. PMID: 24892658
    4. SCN2B is a new candidate gene associated with Brugada syndrome. PMID: 23559163
    5. beta2 is a PS/gamma-secretase substrate, gamma-secretase mediated cleavage of beta2-C-terminal fragment is required for cell-cell adhesion and migration of beta2-expressing cells PMID: 15833746

    顯示更多

    收起更多

  • 相關疾病：
    Atrial fibrillation, familial, 14 (ATFB14)
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Sodium channel auxiliary subunit SCN2B (TC 8.A.17) family
  • 組織特異性：
    Brain specific.
  • 數據庫鏈接：

    HGNC: 10589

    OMIM: 601327

    KEGG: hsa:6327

    STRING: 9606.ENSP00000278947

    UniGene: Hs.129783



主站蜘蛛池模板： 免费三级现频在线观看播放| 亚洲人成网站在线播放2019| 国产在线拍偷自揄拍无码| 亚洲a成人无m网站在线| 亚洲高清国产拍精品26u| 国产卡一卡二无线乱码| 东京热久久综合久久88| 日本最新免费二区三区| 国产亚洲精品国产福app| 免费人成网站视频在线观看国内| 久久久中日ab精品综合 | 中国女人做爰视频| 美女张开腿让人桶| 噜噜噜av久久av苍井空| 天堂资源在线官网| 欧美亚洲国产片在线播放| 草色噜噜噜av在线观看香蕉| 麻豆果冻传媒精品| 高清破外女出血av毛片| 国产在不卡免费一区二区三| 网禁拗女稀缺资源在线观看| 日韩精品成人一区二区三区| 蜜臀久久99精品久久久久久| 亚洲熟女精品中文字幕| 国产一区二区亚洲精品 | 色悠久久久久久久综合网| 国产在视频线精品视频| 成年无码动漫av片在线尤物| 国产免费不卡av在线播放| 国产精品久久久久影院老司| 国产一区二区三区成人欧美日韩在线观看 | 国产山东熟女48嗷嗷叫| 无码人妻精品一区二区蜜桃色欲| 18禁美女黄网站色大片免费看| 精品国产美女av久久久久| 亚洲午夜久久久无码精品网红a片| 国产95在线 | 亚洲| 亚洲人成色4444在线观看| 非洲黑人性xxxx精品| 97免费人妻在线视频| 久久精品无码精品免费专区|