在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SCGN Antibody

  • 中文名稱:
    SCGN兔多克隆抗體
  • 貨號(hào):
    CSB-PA020821GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    SCGN
  • 別名:
    Calbindin like antibody; CALBL antibody; DJ501N12.8 antibody; OTTHUMP00000016124 antibody; Scgn antibody; SECRET antibody; Secretagogin antibody; Secretagogin EF hand calcium binding protein antibody; SEGN antibody; SEGN_HUMAN antibody; Setagin antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SCGN
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn):
    1. the overexpression of SCGN in SW480 human colorectal cancer cells promoted cell apoptosis and inhibited cell migration and invasion. PMID: 29499408
    2. Glucose-dependent de-SUMOylation of tomosyn1 at K298 releases syntaxin1A and controls the amplification of exocytosis in concert with a recently-identified tomosyn1-interacting partner; the Ca(2+)-binding protein secretagogin, which dissociates from tomosyn1 in response to Ca(2+)-raising stimuli and is required for insulin granule trafficking and exocytosis downstream of Ca(2+) influx. PMID: 28325894
    3. secretagogin is a potential biomarker, reflecting stress and islet cell dysfunction in T2D patients PMID: 29702679
    4. Secretagogin-dependent MMP2 release from neurons regulates neuroblast migration. PMID: 28223495
    5. The low SCGN plasma levels in children with ASD probably indicate that SCGN might be implicated in the pathogenesis of autism. However, these data should be treated with caution until further investigations are performed using larger sample sizes to determine whether the decrease in plasma SCGN levels is a mere consequence of autism or it plays a pathogenic role in the disease. PMID: 28492151
    6. Therefore, and considering the desensitization of TRPV1s in diabetic pancreata, a TRPV1-to-secretagogin regulatory axis seems critical to maintain the structural integrity and signal competence of beta-cells. PMID: 28637794
    7. These results suggest SCGN is involved in the chemoresistance of small cell lung cancer under the regulation of miR-494 PMID: 25226615
    8. Scgn is a CaBP expressed in a subpopulation of nociceptive DRG neurons and their processes in the dorsal horn. PMID: 23102406
    9. While secretagogin mRNA was detected in both peripheral mononuclear cells and erythrocytes using reverse-transcription polymerase chain reaction, SCGN protein was only detected in erythrocytes. PMID: 22921511
    10. Data show that the density of secretagogin-positive neurons selectively decreases in the olfactory tract in Alzheimer's disease. PMID: 22474393
    11. Levels of secretagogin correlate with mortality and are useful as predictors of outcome in children with traumatic brain injury. PMID: 21976236
    12. Ddetection of novel calcium-binding protein secretagogin within subgroup of clear-cell renal cell carcinomas. Increased metastasis rates within secretagogin-positive subgroup of clear-cell renal cell carcinomas. PMID: 21288557
    13. Results emphasize the developmentally shared origins of neurons populating the extended amygdala, and suggest that secretagogin can be relevant to the generation of functional modalities in specific neuronal circuitries. PMID: 20529129
    14. Secretagogin might play a role in human non-functional pituitary adenomas. This novel finding may provide clues to clarify the basic molecular mechanisms of pituitary adenoma formation, and to identify new tumor-related markers. PMID: 15237930
    15. two new variants of the recently identified hexa-EF-hand calcium binding protein secretagogin PMID: 15766553
    16. We identified and characterized promoter activity of a human 1498 bp secretagogin sequence upstream the transcription start site. PMID: 17083620

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 組織特異性:
    Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restric
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16941

    OMIM: 609202

    KEGG: hsa:10590

    STRING: 9606.ENSP00000367197

    UniGene: Hs.116428



主站蜘蛛池模板: 男女18禁啪啪无遮挡激烈网站| 日韩卡二卡三卡四卡永久入口 | 最新亚洲中文字幕在线观看| 天天狠天天透天天伊人| 无码少妇一区二区| 中文字幕无线码免费人妻| 国产精品白浆在线观看免费| 欧美裸体xxxx极品| 久久久精品人妻一区二区三区四| 免费观看羞羞视频网站| 中文字幕人妻熟女人妻a片| 亚洲 制服丝袜 中文字幕 在线| 亚洲午夜精品久久久久久app| 无码av无码天堂资源网| 亚洲妇女行蜜桃av网网站| 乱无码伦视频在线观看| 国产精品亚洲综合一区二区三区| 亚洲人成在线观看| 亚洲国产精品13p| 四虎影视在线永久免费观看| 亚洲国产果冻传媒av在线观看| 天堂国产一区二区三区| 男女无遮挡猛进猛出免费观看视频| 欧美成人精品一区二区三区色欲| 一本大道久久久久精品嫩草| 日韩 欧美 国产 一区三| 欧美精品a∨在线观看| 300部国产真实乱| 国产亲子乱弄免费视频| 天堂av无码大芭蕉伊人av不卡| 亚洲国产人在线播放首页| 蜜臀av在线播放| 内射巨臀欧美在线视频| 亚洲一线二线三线品牌精华液久久久 | 搡老熟女老女人一区二区| 少妇午夜福利一区二区| 九九久久精品国产免费看小说| 两性色午夜免费视频| 中文无码熟妇人妻av在线| 国产超碰女人任你爽| 中国6一12呦女精品|