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SCARF2 Antibody

  • 中文名稱：
    SCARF2兔多克隆抗體
  • 貨號：
    CSB-PA070232
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SCARF2
  • 別名：
    SCARF2 antibody; SREC2 antibody; SREPCR antibody; Scavenger receptor class F member 2 antibody; SRECRP-1 antibody; Scavenger receptor expressed by endothelial cells 2 protein antibody; SREC-II antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human SREC-II.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
  • 基因功能參考文獻：
    1. the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2. PMID: 24478002
    2. Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. PMID: 20887961
    3. SRECII binds to SRECI and has a similar tissue distribution pattern PMID: 12154095
  • 相關疾病：
    Van den Ende-Gupta syndrome (VDEGS)
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
  • 數據庫鏈接：

    HGNC: 19869

    OMIM: 600920

    KEGG: hsa:91179

    STRING: 9606.ENSP00000266214

    UniGene: Hs.474251



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