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  4. SCARF1 Antibody

SCARF1 Antibody

  • 中文名稱：
    SCARF1兔多克隆抗體
  • 貨號：
    CSB-PA020769GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SCARF1
  • 別名：
    Acetyl LDL receptor antibody; Endothelial cells scavenger receptor antibody; SCARF1 antibody; Scavenger receptor class F member 1 antibody; Scavenger receptor expressed by endothelial cells 1 antibody; Scavenger receptor expressed by endothelial cells antibody; SREC antibody; SREC-I antibody; SREC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SCARF1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
  • 基因功能參考文獻：
    1. Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes PMID: 25641411
    2. These studies in addition to our earlier findings showed SREC-I to play a primary role in chaperone-associated antigen uptake both through cross priming of MHC class I molecules and entry into the class II pathway. PMID: 25155057
    3. In several assay systems this type F-scavenger receptor, termed SREC-I, bound to cell wall techoic acid in a charge dependent manner and mediated adhesion to nasal epithelial cells in vitro. PMID: 24788600
    4. GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI and SR-BI. Dendritic cells express SREC-I and also bind and internalize GP2. PMID: 21190681
    5. Characterization of the gene and its regulation by a novel transcription factor, endothelial zinc protein-2 PMID: 11978792
    6. SRECI binds to SRECII and has a similar tissue distribution pattern PMID: 12154095

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  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Endothelial cells.
  • 數據庫鏈接：

    HGNC: 16820

    OMIM: 607873

    KEGG: hsa:8578

    STRING: 9606.ENSP00000263071

    UniGene: Hs.647430



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