1. The authors results demonstrate that SNP in the SAMM50 gene is significantly associated with the presence and severity of NAFLD in a Korean populations. PMID: 29271184
2. Findings suggest a significant association between variants in COL13A1, ADIPOQ, SAMM50, and PNPLA3, and risk of NAFLD/elevated transaminase levels in Mexican adults with an admixed ancestry. PMID: 29307798
3. SAMM50 affects the Drp1-dependent mitochondrial morphology. PMID: 27059175
4. downregulation of SAM50 in BCR-ABL-expressing, but not normal CD34(+) human hematopoietic stem and progenitor cells (HSPCs) caused a significant decrease in growth, colony formation, and replating capacity. PMID: 26855047
5. the integrity of MICOS and its efficient interaction with Sam50 are indispensable for cristae organization, which is relevant to mitochondrial function. PMID: 26530328
6. Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD. PMID: 23535911
7. The study describes a novel role of SAM50 in maintaining the mitochondrial shape and the morphology of cristae. PMID: 22252321

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HGNC: 24276

OMIM: 612058

KEGG: hsa:25813

STRING: 9606.ENSP00000345445

UniGene: Hs.505824