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  4. SAMD9L Antibody

SAMD9L Antibody

  • 中文名稱：
    SAMD9L兔多克隆抗體
  • 貨號：
    CSB-PA095524
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SAMD9L
  • 別名：
    SAMD9L antibody; C7orf6 antibody; DRIF2 antibody; KIAA2005 antibody; UEF antibody; Sterile alpha motif domain-containing protein 9-like antibody; SAM domain-containing protein 9-like antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SAMD9L
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in endosome fusion. Mediates down-regulation of growth factor signaling via internalization of growth factor receptors.
  • 基因功能參考文獻：
    1. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms in two unrelated Caucasian families. PMID: 28202457
    2. Missense Mutations in SAMD9L gene is Associated with Ataxia-Pancytopenia Syndrome. PMID: 27259050
    3. The findings highlight a novel tumor-suppressive role of SAMD9L inactivation by somatic mutation and decreased expression in human HBV-related HCC PMID: 25076857
  • 相關疾病：
    Ataxia-pancytopenia syndrome (ATXPC)
  • 亞細胞定位：
    Early endosome.
  • 組織特異性：
    Widely expressed in adult and fetal tissues. Variable expression in tumors. Down-regulated in breast cancer.
  • 數據庫鏈接：

    HGNC: 1349

    OMIM: 159550

    KEGG: hsa:219285

    STRING: 9606.ENSP00000326247

    UniGene: Hs.489118



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