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S100A3 Antibody

  • 中文名稱:
    S100A3兔多克隆抗體
  • 貨號:
    CSB-PA020631GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    S100A3
  • 別名:
    Protein S 100E antibody; Protein S-100E antibody; Protein S100 A3 antibody; Protein S100-A3 antibody; S100 calcium binding protein A3 antibody; S100 calcium-binding protein A3 antibody; S100a3 antibody; S100E antibody; S10A3_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human S100A3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
  • 基因功能參考文獻:
    1. S100A3 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. One disulfide bridge is between Cys30 in the N-terminal pseudo-EF-hand and Cys68 in the C-terminal EF-hand (SS1), and another disulfide bridge attaches Cys99 in the C-terminal coil structure to Cys81 in helix IV (SS2). PMID: 21377473
    3. crystal structure of S100A3 at 1.7-A resolution PMID: 12045193
    4. structure was solved by MIRAS phasing PMID: 12136135
    5. Purification and characterization of the S100A3 protein from human hair cuticles. PMID: 12470658
    6. cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705

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  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    S-100 family
  • 組織特異性:
    Skin specific, specifically expressed at the inner endocuticle of hair fibers.
  • 數據庫鏈接:

    HGNC: 10493

    OMIM: 176992

    KEGG: hsa:6274

    STRING: 9606.ENSP00000357701

    UniGene: Hs.557609



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