在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RTKN Antibody

  • 中文名稱:
    RTKN兔多克隆抗體
  • 貨號:
    CSB-PA020565ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: RTKN antibody at 4.66μg/ml
      Lane 1: A431 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 63, 62, 57 kDa
      Observed band size: 63 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA020565ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA020565ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RTKN Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RTKN
  • 別名:
    Rhotekin antibody; Rtkn antibody; RTKN_HUMAN antibody; RTKN1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Rhotekin protein (304-563AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
  • 基因功能參考文獻:
    1. Let-7a microRNA inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer. PMID: 27498032
    2. RTKN is upregulated in hepatocellular carcinoma.MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma. PMID: 27922690
    3. The RTKN protein is associated with lung cancer in clinic samples and exerts anticancer activity in lung adenocarcinoma cells through inhibiting cell cycle progression and the DNA replication machinery. PMID: 26935528
    4. RTKN could affect the proliferation and metastasis of colon cancer by reducing expression of MCM2/3/5, CDK1/2 and PCNA PMID: 26349972
    5. suggest that interaction of S100A4 and Rhotekin permits S100A4 to complex with RhoA and switch Rho function from stress fiber formation to membrane ruffling to confer an invasive phenotypea PMID: 22964635
    6. Rho/RTKN-mediated NF-kappaB activation leading to cell survival may play a key role in gastric tumorigenesis. PMID: 15316142
    7. overexpression may play a key role in gastric tumorigenesis by conferring cells resistance to apoptosis PMID: 15480428
    8. These results suggest that the RTKN gene is involved in bladder carcinogenesis and progression in bladder carcinoma, indicating that RTKN gene could be a molecular target in cancer therapy. PMID: 15599595
    9. Lin-7B is a binding partner for Rhotekin in the human brain cDNA library PMID: 16979770
    10. SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling PMID: 17546647
    11. Rhotekin forms a complex with vinexin and may play a role at focal adhesions. PMID: 19294487
    12. Loss of miR-145 may provide a selective growth advantage for MCF-7 by targeting RTKN. PMID: 19360360

    顯示更多

    收起更多

  • 組織特異性:
    Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested
  • 數據庫鏈接:

    HGNC: 10466

    OMIM: 602288

    KEGG: hsa:6242

    STRING: 9606.ENSP00000272430

    UniGene: Hs.192854



主站蜘蛛池模板: 无套内射视频囯产| 日产精品卡1卡2卡三卡在线| 秋霞av在线露丝片av无码| 精品国产福利久久久| 中文字幕久久久久人妻| 亚洲一区二区| 唐人社导航福利精品| 国产综合色在线视频区| 国产情侣真实54分钟在线| 久久人人爽人人爽爽久久小说 | 国产精品亚洲一区二区三区| 色欲天天婬色婬香综合网完整版 | 亚洲国产精品av在线播放| 亚洲精品无码不卡在线播放| 337p粉嫩大胆色噜噜噜| 欧美大浪妇猛交饥渴大叫| 日韩精品无码成人专区| 成人女人黄网站免费视频| 精品av综合导航| 国产精品自产拍在线观看| 国产亚洲精品久久久久久久软件| 制服 丝袜 亚洲 中文 综合| 国产爽视频在线观看视频| 亚洲高清毛片一区二区| 精品一区二区三区免费毛片爱| 一本久久a久久精品综合| 人人做人人爽久久久精品| 日韩不卡1卡2卡三卡2021免费| 久久综合九色综合久99| 一本本月无码-| 国产精品午夜福利不卡| 精品美女国产互换人妻| 少妇高潮毛片免费看| 狠狠躁日日躁夜夜躁2022麻豆| 9999国产精品欧美久久久久久 | 久久国产色欲av38| 人妻无码精品久久亚瑟影视| 色拍拍欧美视频在线看| 国产喷水1区2区3区咪咪爱av| 成人国产一区二区三区精品不卡| 中国老熟女重囗味hdxx|