在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RRAGB Antibody

RRAGB Antibody

  • 中文名稱：
    RRAGB兔多克隆抗體
  • 貨號：
    CSB-PA020510GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RRAGB antibody; Ras-related GTP-binding protein B antibody; Rag B antibody; RagB antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RRAGB
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
  • 基因功能參考文獻：
    1. Data suggest DNM2/RRAGB- (or DNM2/RRAGC-)dependent endocytosis of extracellular amino acids (AAs) plays critical role in mTORC1 transport/activation; recruitment of mTORC1 from cytoplasm to lysosome is suppressed by DNM2 inhibition; AA deprivation appears to be main cause of mTORC1 inactivation via DNM2 inhibition. (RHEB = Ras homolog enriched in brain; DNM2 = dynamin II; RRAG = Ras-related GTP binding protein) PMID: 28808055
    2. Inhibition of glutaminolysis prevents GTP loading of RagB and lysosomal translocation and subsequent activation of mTORC1. PMID: 22749528
  • 亞細胞定位：
    Cytoplasm. Lysosome.
  • 蛋白家族：
    GTR/RAG GTP-binding protein family
  • 數據庫鏈接：

    HGNC: 19901

    OMIM: 300725

    KEGG: hsa:10325

    STRING: 9606.ENSP00000262850

    UniGene: Hs.50282



主站蜘蛛池模板： 男人添女人下部高潮视频| 亚洲va天堂va欧美片a在线| 手机在线看片| 日本熟妇人妻xxxxx人hd| 亚洲大色堂人在线无码| 疯狂迎合进入强壮公的视频| 在线精品亚洲第一区焦香| 99re在线播放| 国产成人精品亚洲线观看| 色依依av在线| 亚洲欧美日韩综合久久久| 日本理论片午午伦夜理片2021| 九九99精品久久久久久综合| 精品久久久中文字幕人妻| 中文字幕av无码一区二区三区| 日本乱妇乱子视频网站-百度| 久久人人做人人妻人人玩精品hd| 亚洲国产精品嫩草影院永久| 热99re久久国超精品首页| 亚洲精品久久久久久久蜜桃臀 | 亚洲午夜免费福利视频| 夫前人妻被灌醉侵犯在线| 亚洲欧洲久久av| aⅴ亚洲 日韩 色 图网站 播放 | 97se亚洲精品一区二区| 亚洲综合激情另类专区| 里番本子纯肉侵犯肉全彩无码| 日韩人妻熟女中文字幕a美景之屋 高h纯肉无码视频在线观看 | 在线观看高h无码黄动漫| 国产成人a无码短视频| 狠狠躁天天躁中文字幕| 亚洲情xo亚洲色xo无码| 日日橹狠狠爱欧美视频| 中文字幕人妻丝袜成熟乱 | 久久婷婷色综合老司机| 亚洲精品久久久久久久蜜桃臀| 天堂中文最新版在线官网在线| 波多野结衣av在线无码中文18| 无码三级国产三级在线电影| 欧美日本日韩| 熟女人妻在线视频|