在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RRAGB Antibody

RRAGB Antibody

  • 中文名稱：
    RRAGB兔多克隆抗體
  • 貨號：
    CSB-PA020510GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RRAGB antibody; Ras-related GTP-binding protein B antibody; Rag B antibody; RagB antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RRAGB
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
  • 基因功能參考文獻：
    1. Data suggest DNM2/RRAGB- (or DNM2/RRAGC-)dependent endocytosis of extracellular amino acids (AAs) plays critical role in mTORC1 transport/activation; recruitment of mTORC1 from cytoplasm to lysosome is suppressed by DNM2 inhibition; AA deprivation appears to be main cause of mTORC1 inactivation via DNM2 inhibition. (RHEB = Ras homolog enriched in brain; DNM2 = dynamin II; RRAG = Ras-related GTP binding protein) PMID: 28808055
    2. Inhibition of glutaminolysis prevents GTP loading of RagB and lysosomal translocation and subsequent activation of mTORC1. PMID: 22749528
  • 亞細胞定位：
    Cytoplasm. Lysosome.
  • 蛋白家族：
    GTR/RAG GTP-binding protein family
  • 數據庫鏈接：

    HGNC: 19901

    OMIM: 300725

    KEGG: hsa:10325

    STRING: 9606.ENSP00000262850

    UniGene: Hs.50282



主站蜘蛛池模板： 无码av中文字幕免费放| 亚洲精品无码不卡| 丰满岳跪趴高撅肥臀尤物在线观看| 高潮喷吹一区二区在线观看| 18禁无遮挡肉动漫在线播放观看| 亚洲国产福利一区二区三区| 欧美成人精品三级网站| 久久亚洲精品无码网站| 好硬好湿好爽好深视频| 久久久日韩精品一区二区三区| 亚洲午夜福利在线观看| 免费无码a片一区二三区| 久久无码中文字幕免费影院| a在线视频v视频| 欧美性插b在线视频网站| 国产高潮抽搐喷水高清| 嫖妓大龄熟妇正在播放| 国产奶头好大揉着好爽视频 | 人妻少妇久久中文字幕| 国产麻豆精品一区| 玩弄漂亮少妇高潮白浆| 亚洲中文字幕乱码熟女在线| 国产成人av一区二区三区在线观看 | 亚洲精品第一区二区三区| 国产黄a三级三级三级av在线看| 一本一道波多野结衣一区| 日本亚欧热亚洲乱色视频| 欧美性受xxxxzooz乱毛| 毛多水多www偷窥小便| 无码精品日韩中文字幕| 色香阁综合无码国产在线| 国产亚洲精品成人aa片新蒲金| 欧美性受xxxx黑人xyx性爽 | 国产精品美女www爽爽爽视频| 日韩人妻无码精品系列| 少妇人妻偷人精品无码视频新浪| 国产对白老熟女正在播放| 中文精品一卡2卡3卡4卡国色| 欧洲亚洲色视频综合在线| 亚洲国产欧洲综合997久久| 久艹视频免费看|