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RPS27 Antibody

  • 中文名稱:
    RPS27兔多克隆抗體
  • 貨號:
    CSB-PA020419ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA020419ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RPS27 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RPS27
  • 別名:
    2610206D02Rik antibody; 3200001M24Rik antibody; 40S ribosomal protein S27 antibody; C530005D02Rik antibody; Metallopan stimulin 1 antibody; Metallopan-stimulin 1 antibody; Metallopanstimulin 1 antibody; Metallopanstimulin1 antibody; MPS 1 antibody; MPS-1 antibody; MPS1 antibody; pmn antibody; Ribosomal protein S27 antibody; Ribosomal protein S27 metallopanstimulin 1 antibody; rps27 antibody; RS27_HUMAN antibody; S27 antibody; snoRNA MBI 112 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human 40S ribosomal protein S27 protein (1-84AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs.
  • 基因功能參考文獻:
    1. Chloride anion behaves as a signaling effector for CFTR in the modulation of RPS27 expression. PMID: 28941802
    2. reveal how Mps1 dynamically modifies kinetochores to correct improper attachments and ensure faithful chromosome segregation PMID: 28441529
    3. MPS1 is a new marker of Purkinje Cells. PMID: 26708598
    4. We identified frequent recurrent (i.e. hotspot) mutation in the 5' untranslated region of RPS27 in ~10% of melanoma samples PMID: 24913145
    5. The data on genome context analysis indicates that the presence of MPS-1 in the blood is an indicator of oncogenesis PMID: 22798506
    6. This work is consistent with a critical role of RPMPS-1/S27 in the life cycle of various viruses and shows that disruption of viral ZFPs is potentially important to control and prevent deathly viral diseases PMID: 21518817
    7. study reveals a multilevel interplay between RPS27L/S27 and p53-MDM2 axis, with RPS27L functioning as a p53 target, a MDM2 substrate and a p53 regulator PMID: 21170087
    8. When MPS-1 is overexpressed, it has an extraribosomal function as a strong inhibitor of HNSCC tumor cell growth, which may be exerted by reduced paxillin gene expression. PMID: 19642098
    9. MPS-1 was overexpressed in 86% of the gastric cancer tissues and all gastric cancer cells. MPS-1 expression was significantly increased and corresponded with the tumor-node-metastasis clinical stage, and was significantly higher in the late stage. PMID: 16914586

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  • 相關疾病:
    Diamond-Blackfan anemia 17 (DBA17)
  • 蛋白家族:
    Eukaryotic ribosomal protein eS27 family
  • 組織特異性:
    Expressed in a wide variety of actively proliferating cells and tumor tissues.
  • 數據庫鏈接:

    HGNC: 10416

    OMIM: 603702

    KEGG: hsa:6232

    STRING: 9606.ENSP00000357555

    UniGene: Hs.546291



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