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RPLP2 Antibody

  • 中文名稱:
    RPLP2兔多克隆抗體
  • 貨號(hào):
    CSB-PA040245
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    RPLP2
  • 別名:
    2700049I22Rik antibody; 60S acidic ribosomal protein P2 antibody; Acidic ribosomal phosphoprotein P2 antibody; D11S2243E antibody; LP2 antibody; MGC71408 antibody; OTTMUSP00000029428 antibody; OTTMUSP00000029429 antibody; OTTMUSP00000029430 antibody; P2 antibody; Renal carcinoma antigen NY-REN-44 antibody; Ribosomal protein P2 antibody; Ribosomal protein, large, P2 antibody; RLA2_HUMAN antibody; rplP2 antibody; RPP2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Ribosomal Protein LP2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays an important role in the elongation step of protein synthesis.
  • 基因功能參考文獻(xiàn):
    1. Collectively, the present results suggest that PhoRpp21 binds the loop between P11 and P12 helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity. PMID: 27810361
    2. Results show that the conserved C-terminal segment of P2 from three different eukaryotic species- Human, Plasmodium falciparum and Toxoplasma gondii is intrinsically disordered. PMID: 25412900
    3. relevance of the observed cross-reactive IgE autoantibodies against P2 proteins in systemic lupus eryth remains to be elucidated PMID: 21410706
    4. the eukaryotic stalk protein P2 forms a symmetric homodimer in solution, and is structurally distinct from the bacterial counterpart L12 homodimer. PMID: 20385603
    5. Ribosomal protein P2 has been identified as a novel substrate of GRK2 in HEK-293 cells where P2 phosphorylation is increased following agonist stimulation of the beta 2-adrenergic receptor under conditions of tyrosine kinase PKC and PKA inhibition. PMID: 12379128
    6. Antisense-mediated depletion may disrupt the proteome of cancer cells. PMID: 14981896
    7. Distinct roles for CD39 and P2-purinergic signaling in both tissue remodeling and fibrogenesis with respect to human pancreatic diseases. PMID: 16920697

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  • 蛋白家族:
    Eukaryotic ribosomal protein P1/P2 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10377

    OMIM: 180530

    KEGG: hsa:6181

    STRING: 9606.ENSP00000322419

    UniGene: Hs.437594



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