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  4. RPL35A Antibody, HRP conjugated

RPL35A Antibody, HRP conjugated

  • 中文名稱：
    RPL35A兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA020248LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RPL35A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPL35A
  • 別名：
    60S ribosomal protein L35a antibody; Cell growth-inhibiting gene 33 protein antibody; DBA5 antibody; L35A antibody; Ribosomal Protein L35a antibody; RL35A_HUMAN antibody; RPL35A antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human 60S ribosomal protein L35a (1-110AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
  • 基因功能參考文獻(xiàn)：
    1. We identified 85 overlapping deletions, of which six included the RPL35A gene and all should be had Diamond-Blackfan anemia (DBA).we sequenced the remaining RNF168 gene and examined her fibroblast culture for a DNA double strand break repair deficiency. These results were normal, indicating that the immunodeficiency is unlikely to result from a RNF168 deficiency. PMID: 28432740
    2. Studies identified deletions at known Diamond-Blackfan anemia (DBA)-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A. PMID: 22045982
    3. Inhibition of cell death by ribosomal protein L35a. PMID: 12175552
    4. analysis of 2 Diamond-Blackfan anemia (DBA) patients with chromosome 3q deletions identified RPL35A as a potential DBA gene PMID: 18535205
  • 相關(guān)疾病：
    Diamond-Blackfan anemia 5 (DBA5)
  • 蛋白家族：
    Eukaryotic ribosomal protein eL33 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10345

    OMIM: 180468

    KEGG: hsa:6165

    STRING: 9606.ENSP00000393393

    UniGene: Hs.529631



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