在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RPL10 Antibody

  • 中文名稱:
    RPL10兔多克隆抗體
  • 貨號:
    CSB-PA012538
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from K562 cells, treated with Insulin (0.01u/ml, 15mins), using 60S Ribosomal Protein L10 antibody.
    • Western blot analysis of extracts from K562 cells (Lane 2), JK cells (Lane 3) and 293 cells (Lane 4), using 60S Ribosomal Protein L10 antiobdy. The lane on the left is treated with synthesized peptide.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) RPL10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RPL10
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human 60S Ribosomal Protein L10.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.
  • 基因功能參考文獻(xiàn):
    1. The regulation of reactive oxygen species level by mitochondrial RPL10 is one of the major extra-ribosomal functions in pancreatic cancer cells, which could be used as an indicator for the tumorigenesis of pancreatic cancer. PMID: 30172100
    2. there are 7 mutations in RPL10 in 344 patients, or a mutation frequency of 2% PMID: 28428269
    3. A rare de novo mutation K78E is associated with severe syndromic intellectual disability and epilepsy. PMID: 29066376
    4. Mitochondrial Ribosomal Protein L10 regulates cyclin B1/Cdk1 (cyclin-dependent kinase 1) activity and mitochondrial protein synthesis in mammalian cells PMID: 27726420
    5. Our results expand the mutational and clinical spectrum of RPL10 identifying a new genetic cause of SED and highlight the emerging role of ribosomal proteins in the pathogenesis of neurodevelopmental disorders. PMID: 26290468
    6. report confirms the implication of RPL10 mutations in neurodevelopmental disorders and extends the associated clinical spectrum from autism to syndromic intellectual disability PMID: 25846674
    7. A mutation within the conserved N-terminal end of RPL10, a protein in close proximity to the peptidyl transferase active site of the 60S ribosomal subunit, causes severe defects in brain formation and function. PMID: 25316788
    8. Mutations affect the ribosomal proteins RPL5 and RPL10 in 12 of 122 (9.8%) pediatric T-cell acute lymphoblastic leukemias, with recurrent alterations of Arg98 in RPL10. PMID: 23263491
    9. mutation analysis of RPL10 in German patients with autism spectrum disorder PMID: 21567917
    10. Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism PMID: 16940977
    11. QM binds to c-yes at the SH3 domain in tumor cell lines PMID: 12138090
    12. Reduction of QM protein expression correlates with tumor grade in prostatic adenocarcinoma PMID: 16331298
    13. Xq28 (QM gene) may be involved in ovary failure. PMID: 17566674
    14. A hexagonal crystal of L10CD was obtained by the sitting-drop vapour-diffusion method. The L10CD crystal diffracted to 2.5 A resolution and belongs to space group P3(1)21 or P3(2)21. PMID: 18007048
    15. Characteristic interactions among Arg90-Trp171-Arg139 guide the C-terminal part outside of the central fold PMID: 18258260
    16. Our results suggest that RPL10 has no major effect on the susceptibility to autism spectrum disorders PMID: 19166581

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Autism, X-linked 5 (AUTSX5); Mental retardation, X-linked, syndromic, 35 (MRXS35)
  • 蛋白家族:
    Universal ribosomal protein uL16 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10298

    OMIM: 300847

    KEGG: hsa:6134

    STRING: 9606.ENSP00000341730

    UniGene: Hs.534404



主站蜘蛛池模板: 寂寞少妇做spa按摩无码| 48沈阳熟女高潮嗷嗷叫| 性xxxx视频播放免费| 日本新janpanese乱熟| 色 成人 亚洲| 青青草无码精品伊人久久| 国产精品久久久久久福利| 国产69精品久久久久久久| 人妻少妇乱子伦精品| 护士奶头又大又软又好摸| 国产日产人妻精品精品| 中文在线а√在线| 亚洲成av人在线播放无码| 国产在线拍揄自揄视频网试看| 日本xxxx片免费观看| 亚洲精品国偷自产在线| 成人综合网站| 欧洲 亚洲 国产图片综合| 免费一区二区无码东京热 | 国产成人精品午夜福利在线播放| 超薄丝袜足j好爽在线观看| 欧美潮喷少妇100| 老太脱裤让老头玩ⅹxxxx| 猫咪www免费人成网站无码| 国内精品久久久久影院优| 丰满妇女强制高潮18xxxx| 日本三级欧美三级人妇视频黑白配| 国产成人免费无码av在线播放| 天天综合网亚在线| 国产男女猛烈无遮挡免费视频网站| 日本午夜免费福利视频| 国产男生午夜福利免费网站| 欧美自拍亚洲综合丝袜| 午夜天堂一区人妻| 亚洲欧美国产毛片在线| 日本熟妇hdsex视频| 欧美最猛黑人xxxxx猛交| 精品久久久噜噜噜久久久| 精品一卡二卡三卡四卡网站| 亚洲成aⅴ人片在线观| 亚洲色偷拍另类无码专区|