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  4. RPIA Antibody，Biotin conjugated

RPIA Antibody，Biotin conjugated

  • 中文名稱：
    RPIA兔多克隆抗體，Biotin偶聯
  • 貨號：
    CSB-PA020104LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RPIA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPIA
  • 別名：
    EC 5.3.1.6 antibody; MGC103524 antibody; Phosphoriboisomerase A antibody; Phosphoriboisomerase antibody; Ribose 5 phosphate isomerase antibody; ribose 5-phosphate epimerase antibody; ribose 5-phosphate isomerase A antibody; Ribose-5-phosphate isomerase antibody; RPI antibody; rpiA antibody; RPIA_HUMAN antibody; zgc:103524 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ribose-5-phosphate isomerase protein (1-311AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. The results are consistent with a model in which RPIA suppresses autophagy and LC3 processing by modulation of redox signaling. PMID: 27328773
    2. CRC cells that overexpressed miR124 or with knockdown of RPIA or PRPS1 had reduced DNA synthesis and proliferation, whereas cells incubated with an inhibitor of miR124 had significantly increased DNA synthesis and proliferation and formed more colonies. PMID: 26248089
    3. In this work, through an in silico comparative analysis between the genomes of Leishmania major and Homo sapiens, the enzyme ribose 5-phosphate isomerase (R5PI) was indicated as a promising molecular target. PMID: 25528729
    4. Study provides new insight into the molecular mechanisms by which RPIA overexpression can induce oncogenesis in hepatocellular carcinoma. PMID: 25429733
    5. RPI is the second known inborn error in the reversible phase of the pentose-phosphate-pathway, confirming that defects in pentose and polyol metabolism constitute a new area of inborn metabolic disorders PMID: 14988808

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  • 相關疾病：
    Ribose 5-phosphate isomerase deficiency (RPID)
  • 蛋白家族：
    Ribose 5-phosphate isomerase family
  • 數據庫鏈接：

    HGNC: 10297

    OMIM: 180430

    KEGG: hsa:22934

    STRING: 9606.ENSP00000283646

    UniGene: Hs.469264



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