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RPAP2 Antibody

  • 中文名稱:
    RPAP2兔多克隆抗體
  • 貨號:
    CSB-PA020095GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    RPAP2 antibody; C1orf82 antibody; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 antibody; EC 3.1.3.16 antibody; RNA polymerase II-associated protein 2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RPAP2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
  • 基因功能參考文獻(xiàn):
    1. These results suggest that RPAP2 controls Pol II activity through a direct interaction with Rpb6 PMID: 25639305
    2. During transcription of snRNA genes, Ser7 phosphorylation facilitates recruitment of RPAP2, which in turn both recruits Integrator and dephosphorylates Ser5. PMID: 22137580
  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.
  • 蛋白家族:
    RPAP2 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 25791

    OMIM: 611476

    KEGG: hsa:79871

    STRING: 9606.ENSP00000359368

    UniGene: Hs.444421



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