在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ROS1 Antibody, HRP conjugated

ROS1 Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    ROS1兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA874445LB01DOA
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Arabidopsis thaliana ROS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ROS1 antibody; DML1 antibody; At2g36490 antibody; F1O11.12 antibody; DNA glycosylase/AP lyase ROS1 antibody; EC 4.2.99.18 antibody; DEMETER-like protein 1 antibody; Protein REPRESSOR OF SILENCING 1 antibody; Protein ROS1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
  • 免疫原種屬：
    Arabidopsis thaliana
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity. Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate. Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair.
  • 基因功能參考文獻：
    1. ound that DOGL4 negatively affects seed dormancy and response to the phytohormone abscisic acid and that ROS1 controls these processes by regulating DOGL4 PMID: 30266793
    2. Results provide evidence that ROS1 expression is regulated by MET18 which is required for its activity. ROS1 binds to the iron-sulfur cluster of MET18. PMID: 27193999
    3. ROS1 preferentially targets transposable elements (TEs) and intergenic regions. Compared with most TEs, ROS1-targeted TEs are closer to protein coding genes, suggesting that ROS1 may prevent DNA methylation spreading from TEs to nearby genes. PMID: 27797352
    4. Transgenic tobacco overexpressing AtROS1 showed tolerance to salt stress that could have been due to the higher expression levels of the genes encoding enzymes of the flavonoid biosynthetic and antioxidant pathways. PMID: 26116024
    5. Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation. PMID: 26492035
    6. We propose that the ROS1 locus functions as an epigenetic rheostat, tuning the level of demethylase activity in response to methylation alterations, thus ensuring epigenomic stability. PMID: 25826366
    7. ROS1, DML2, and DML3 play a role in fungal disease resistance in Arabidopsis PMID: 25228471
    8. ROS1 mediated DNA demethylation combats the activity of RNA-directed DNA methylation to influence the initiation of stomatal lineage cells. PMID: 24898766
    9. Data indicate that H3K9 dimethylation level in mutants ros1 fpgs1 (folylpolyglutamate synthase 1) was clearly reduced. PMID: 23881414
    10. the Arabidopsis RdDM pathway has an antisilencing function due to its role in maintaining ROS1 expression PMID: 22733760
    11. The polalpha/incurvata2 (icu2) gene was isolated as one ros1 suppressor because its mutation leads to the reactivation of the silenced 35S-NPTII gene. PMID: 19769574
    12. Data suggest that a function of REPRESSOR OF SILENCING 1 (ROS1) and DEMETER is to initiate erasure of 5-meC through a base excision repair process and provide strong biochemical evidence for the existence of an active DNA demethylation pathway in plants. PMID: 16624880
    13. These results demonstrate that ROS1 is a 5-methylcytosine DNA glycosylase/lyase important for active DNA demethylation in Arabidopsis. PMID: 16864782
    14. CpXpG and CpXpX sites become heavily methylated in the ros1 mutant. PMID: 17208187
    15. ROS1 removes methylation that has multiple, independent origins, including de novo methylation directed by RDR2-dependent and -independent RNAi pathways. PMID: 17951456
    16. Results suggest that ROS1 specificity arises by a combination of selective recognition at the active site and thermodynamic stability of the target base. PMID: 19443451

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    DNA glycosylase family, DEMETER subfamily
  • 組織特異性：
    Expressed ubiquitously in both vegetative and reproductive organs.
  • 數(shù)據(jù)庫鏈接：

    KEGG: ath:AT2G36490

    STRING: 3702.AT2G36490.1

    UniGene: At.14091



主站蜘蛛池模板： 天天狠天天透天干天干| 高中生自慰www网站| 免费观看全黄做爰的视频| 国产薄丝脚交视频在线观看| 中文字幕av伊人av无码av狼人 | 国产jk白丝在线观看免费| 黄a大片av永久免费| 亚洲国产天堂久久综合| av毛片无码中文字幕不卡 | 亚洲aⅴ天堂av天堂无码 | 久久精品伊人一区二区三区| 久久精品一区二区三区中文字幕| 亚洲国产精品久久亚洲精品| 日本欧美一区二区三区在线播放 | 亚洲国产精品一区二区成人片国内| 精品国产sm最大网免费站| 欧美成人va免费大片视频| 777米奇影院狠狠色| 欧美噜噜久久久xxx| 国产精品毛片a∨一区二区三区| 99国产在线精品视频| 青青草国产精品久久久久| 欧美内射深喉中文字幕| 偷看农村女人做爰毛片色| 国内芒果精品自线一区2021| 欧美牲交a欧美牲交aⅴ| 国产精品兄妹在线观看麻豆| 久久亚洲人成综合网| 日韩人妻少妇一区二区三区| 国产精品免费看久久久| 国产亚洲精品久久久久久久软件 | 亚洲成aⅴ人最新无码| 亚洲色成人一区二区三区| 成人欧美一区二区三区| 国产人妻鲁鲁一区二区| 久久69精品久久久久久hb| 2019日韩中文字幕mv| av片在线观看免费| 国产在线乱码一区二区三区| 国产精品免费久久久久电影| 欧美xxxx做受欧美|