在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ROS1 Antibody, HRP conjugated

ROS1 Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    ROS1兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA874445LB01DOA
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Arabidopsis thaliana ROS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ROS1 antibody; DML1 antibody; At2g36490 antibody; F1O11.12 antibody; DNA glycosylase/AP lyase ROS1 antibody; EC 4.2.99.18 antibody; DEMETER-like protein 1 antibody; Protein REPRESSOR OF SILENCING 1 antibody; Protein ROS1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
  • 免疫原種屬：
    Arabidopsis thaliana
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity. Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate. Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair.
  • 基因功能參考文獻：
    1. ound that DOGL4 negatively affects seed dormancy and response to the phytohormone abscisic acid and that ROS1 controls these processes by regulating DOGL4 PMID: 30266793
    2. Results provide evidence that ROS1 expression is regulated by MET18 which is required for its activity. ROS1 binds to the iron-sulfur cluster of MET18. PMID: 27193999
    3. ROS1 preferentially targets transposable elements (TEs) and intergenic regions. Compared with most TEs, ROS1-targeted TEs are closer to protein coding genes, suggesting that ROS1 may prevent DNA methylation spreading from TEs to nearby genes. PMID: 27797352
    4. Transgenic tobacco overexpressing AtROS1 showed tolerance to salt stress that could have been due to the higher expression levels of the genes encoding enzymes of the flavonoid biosynthetic and antioxidant pathways. PMID: 26116024
    5. Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation. PMID: 26492035
    6. We propose that the ROS1 locus functions as an epigenetic rheostat, tuning the level of demethylase activity in response to methylation alterations, thus ensuring epigenomic stability. PMID: 25826366
    7. ROS1, DML2, and DML3 play a role in fungal disease resistance in Arabidopsis PMID: 25228471
    8. ROS1 mediated DNA demethylation combats the activity of RNA-directed DNA methylation to influence the initiation of stomatal lineage cells. PMID: 24898766
    9. Data indicate that H3K9 dimethylation level in mutants ros1 fpgs1 (folylpolyglutamate synthase 1) was clearly reduced. PMID: 23881414
    10. the Arabidopsis RdDM pathway has an antisilencing function due to its role in maintaining ROS1 expression PMID: 22733760
    11. The polalpha/incurvata2 (icu2) gene was isolated as one ros1 suppressor because its mutation leads to the reactivation of the silenced 35S-NPTII gene. PMID: 19769574
    12. Data suggest that a function of REPRESSOR OF SILENCING 1 (ROS1) and DEMETER is to initiate erasure of 5-meC through a base excision repair process and provide strong biochemical evidence for the existence of an active DNA demethylation pathway in plants. PMID: 16624880
    13. These results demonstrate that ROS1 is a 5-methylcytosine DNA glycosylase/lyase important for active DNA demethylation in Arabidopsis. PMID: 16864782
    14. CpXpG and CpXpX sites become heavily methylated in the ros1 mutant. PMID: 17208187
    15. ROS1 removes methylation that has multiple, independent origins, including de novo methylation directed by RDR2-dependent and -independent RNAi pathways. PMID: 17951456
    16. Results suggest that ROS1 specificity arises by a combination of selective recognition at the active site and thermodynamic stability of the target base. PMID: 19443451

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    DNA glycosylase family, DEMETER subfamily
  • 組織特異性：
    Expressed ubiquitously in both vegetative and reproductive organs.
  • 數(shù)據(jù)庫鏈接：

    KEGG: ath:AT2G36490

    STRING: 3702.AT2G36490.1

    UniGene: At.14091



主站蜘蛛池模板： 欧美变态另类xxxx| 国产熟妇精品高潮一区二区三区| 国产精品麻豆成人av网| 色欲av久久综合人妻无码| 亚洲国产精品无码久久久蜜芽| 又硬又粗进去好爽免费| a在线视频v视频| 狼人无码精华av午夜精品| 亚洲日韩av一区二区三区中文| 中国女人大白屁股ass| 国产成人av一区二区三区无码| 久视频精品线在线观看| 中国6一12呦女精品| 国内大量偷窥精品视频| 国产午国产午夜精华 免费| 欧美不卡一卡二卡三卡| 无码免费无线观看在线视| 永久免费观看美女裸体视频的网站| 无人区乱码区1卡2卡三卡网站| 国产sm重味一区二区三区 | 成人无码精品1区2区3区免费看| 国产在线国偷精品免费看| 国产美女极度色诱视频www| 人人妻人人澡人人爽欧美一区九九| 国产成人精品久久一区二区三区 | 国产精品久久| 国产精品久久毛片av大全日韩| 国产一区二区三区| 免费毛片手机在线播放| 免免费国产aaaaa片| 成人性生交大片免费看r链接 | 久久影院午夜伦手机不四虎卡| 国产精品扒开腿做爽爽爽a片唱戏| 真人二十三式性视频(动)| 欧美熟妇xxxxx欧美老妇不卡| 国产精品有码无码av在线播放| 无码中出人妻中文字幕av| 性色香蕉av久久久天天网| 国产精品久久久久久久久ktv| 国产真实乱对白精彩| 国产成人剧情av麻豆果冻|