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RORB Antibody, FITC conjugated

  • 中文名稱:
    RORB兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA821694LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RORB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RORB
  • 別名:
    bA133M9.1 antibody; NR1F2 antibody; Nuclear receptor ROR-beta antibody; Nuclear receptor RZR beta antibody; Nuclear receptor RZR-beta antibody; Nuclear receptor subfamily 1 group F member 2 antibody; OTTHUMP00000021486 antibody; RAR related orphan receptor B antibody; RAR related orphan receptor beta antibody; Retinoic acid binding receptor beta antibody; Retinoid-related orphan receptor-beta antibody; ROR BETA antibody; Rorb antibody; RORB_HUMAN antibody; RZR BETA antibody; RZRB antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Nuclear receptor ROR-beta protein (1-269AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity.; Isoform 1 is critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina. Regulates the expression of PTF1A synergistically with FOXN4.
  • 亞細胞定位:
    Nucleus, nucleoplasm.
  • 蛋白家族:
    Nuclear hormone receptor family, NR1 subfamily
  • 數據庫鏈接:

    HGNC: 10259

    OMIM: 601972

    STRING: 9606.ENSP00000366093

    UniGene: Hs.494178



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