在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RNASEH2B Antibody

  • 中文名稱:
    RNASEH2B兔多克隆抗體
  • 貨號:
    CSB-PA019806GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    RNASEH2B
  • 別名:
    RNASEH2B antibody; DLEU8 antibody; Ribonuclease H2 subunit B antibody; RNase H2 subunit B antibody; Aicardi-Goutieres syndrome 2 protein antibody; AGS2 antibody; Deleted in lymphocytic leukemia 8 antibody; Ribonuclease HI subunit B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RNASEH2B
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
  • 基因功能參考文獻:
    1. Results implicate rare variants in the Aicardi-Goutieres syndrome genes ADAR and RNASEH2B and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis, consistent with a genetic basis underlying inflammation-driven malignant transformation in glioma and prostate carcinoma development. PMID: 29030706
    2. This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2B in patients with Aicardi-Goutieres Syndrome. PMID: 27643693
    3. Aicardi-Goutieres syndrome 2 is caused by mutations in the ribonuclease H2 subunit B gene RNASEH2B. PMID: 25906927
    4. RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B-dependent manner. PMID: 24986920
    5. A genome-wide search for homozygosity in Aicardi-Goutieres syndrome patients in the Faroe Islands revealed one single 15.6 Mb region of homozygosity on chromosome 13, which included RNASEH2B, where a splice site mutation c.322-3C>G was identified. PMID: 22882256
    6. This study demonistrated that ribonuclease H2 mutation releated to Aicardi-Goutieres syndrome. PMID: 21862834
    7. Congenital infection is seen with preserved neurological function, most frequently due to RNASEH2B mutations. PMID: 18422679
    8. Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the B subunit of RNase H2. PMID: 19015152
    9. patients with genetic deficiency develop the spontaneous inflammatory myocarditis PMID: 19120481

    顯示更多

    收起更多

  • 相關疾病:
    Aicardi-Goutieres syndrome 2 (AGS2)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    RNase H2 subunit B family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 25671

    OMIM: 610181

    KEGG: hsa:79621

    STRING: 9606.ENSP00000337623

    UniGene: Hs.306291



主站蜘蛛池模板: 人妻少妇精品久久久久久| 综合色一色综合久久网| 中文字幕亚洲欧美在线不卡| 色吊丝av中文字幕| 国产成人综合久久精品推下载| 国内精品美女a∨在线播放| 人成午夜免费视频无码| 国产精品爽爽久久久久久| 日韩精品无码视频一区二区蜜桃| 天堂在/线中文在线资源8| 国产精品久久久久无码av1| 国产无遮挡aaa片爽爽 | 黑人巨大跨种族video| 亚洲精品综合一区二区三| 亚洲人成网站18禁止一区| 唐人社导航福利精品| 精品成人免费一区二区不卡| 中文字幕久久精品一区二区三区| 奶头好大狂揉60分钟视频 | 国产成人精品一区二区三区无码| 国产区女主播在线观看| 中文天堂最新版在线www| 在线观看国产精品av| 中文字幕亚洲情99在线| 国精品无码一区二区三区在线蜜臀 | 亚洲久久久久久中文字幕| 日韩精品成人无码专区免费| 久久精品中文字幕大胸| 超碰97人人做人人爱亚洲尤物| 在线精品无码字幕无码av| 精品人妻av一区二区三区| 国产亚洲精品久久久久秋霞不卡| 高潮射精日本韩国在线播放| 亚洲成av人片在www色猫咪| 国产超碰人人爽人人做| 亚洲高清无码加勒比| 亚洲国产欧美在线成人aaaa| 99久久精品无码一区二区三区| 国产丝袜足j在线视频播放| √天堂资源中文| 国产伦精品免编号公布|