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RMND5A Antibody

  • 中文名稱:
    RMND5A兔多克隆抗體
  • 貨號:
    CSB-PA875693LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA875693LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RMND5A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RMND5A
  • 別名:
    RMND5A antibody; E3 ubiquitin-protein transferase RMND5A antibody; EC 2.3.2.27 antibody; P44CTLH antibody; Protein RMD5 homolog A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein RMD5 homolog A protein (1-391AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,RMND5A Antibody (CSB-PA875693LA01HU),的標記方式是Non-conjugated。對于RMND5A Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA875693LB01HU RMND5A Antibody, HRP conjugated ELISA
    FITC CSB-PA875693LC01HU RMND5A Antibody, FITC conjugated
    Biotin CSB-PA875693LD01HU RMND5A Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
  • 基因功能參考文獻:
    1. Duplications of this region involving RMND5A, whose product contains a C-terminal to lis homology (LisH) domain, have not previously been associated with a defined phenotype but may present insight into encephalocele formation. PMID: 22681319
    2. RanBPM, ARMC8alpha, ARMC8beta, Muskelin, p48EMLP, and p44CTLH form complexes in cells. PMID: 17467196
  • 亞細胞定位:
    Nucleus, nucleoplasm. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 25850

    KEGG: hsa:64795

    STRING: 9606.ENSP00000283632

    UniGene: Hs.424184



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