在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RLN3 Antibody

  • 中文名稱:
    RLN3兔多克隆抗體
  • 貨號(hào):
    CSB-PA006898
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    RLN3
  • 別名:
    RLN3 antibody; INSL7 antibody; RXN3 antibody; ZINS4 antibody; UNQ6188/PRO20213 antibody; Relaxin-3 antibody; Insulin-like peptide INSL7 antibody; Insulin-like peptide 7 antibody; Prorelaxin H3) [Cleaved into: Relaxin-3 B chain; Relaxin-3 A chain] antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Relaxin 3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.
  • 基因功能參考文獻(xiàn):
    1. Serum level of relaxin-3 hormone is an important mediator in the pathophysiological process of normal puberty being significantly decreased in males with delayed puberty. PMID: 28786126
    2. Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. PMID: 27498038
    3. the relaxin-3 B-chain C-terminus changes from the original folding-back conformation to an extended conformation during binding with RXFP3, to allow its B27Trp and B26Arg residues to interact with the Trp138 and Glu141 residues of RXFP3, respectively. PMID: 27193232
    4. In a population of acute HF patients, admission relaxin serum levels were associated with clinical and echocardiographic markers of pulmonary hypertension, RV dysfunction, and overload, suggesting a role for circulating relaxin as a biomarker in this setting. PMID: 27488261
    5. the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 PMID: 27353281
    6. Relaxin-3 is a high-efficacy agonist at RXFP4 with a comparable signal transduction profile to INSL5. PMID: 27888281
    7. Serum concentrations of relaxin showed a positive association to duration of gestation among women with miscarriage but no association to duration of gestation among women with spontaneous onset of labour. PMID: 26272327
    8. Review of research depicts the connection of relaxin-3 with phenomena such as feeding behavior, spatial memory, sleep/wake cycle or modulation of pituitary gland hormone secretion. PMID: 24988606
    9. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor PMID: 24641548
    10. Glu141 and Asp145 of the RXFP3 interact with the highly conserved arginine residues of relaxin-3. PMID: 24615237
    11. Mutant relaxin-3 shows a significant decrease in receptor-activation potency towards RXFP4. PMID: 24802387
    12. Relaxin-2 or relaxin-3 levels are not related to component traits in patients with diabetes. PMID: 23994775
    13. metabolic syndrome is associated with increased serum relaxin-3 levels in women PMID: 23018057
    14. [review] Relaxin-3 (RXF3P) is expressed within GABA neurons of the brainstem including an area known as the nucleus incertus; ascending relaxin-3 projections innervate a broad range of RXFP3-rich forebrain areas. PMID: 21693186
    15. H3 relaxin exerts antifibrotic actions via RXFP1 receptor PMID: 21229994
    16. Relaxin-3 and receptors in the human and rhesus brain and reproductive tissues. PMID: 19778557
    17. relaxin-3/INSL7 is a ligand for GPCR142 PMID: 14522967
    18. GPCR135 is the receptor for relaxin-3 PMID: 14522968
    19. RLN3 chimeric peptide is a potential tool to study in vivo function of GPCR135. PMID: 15465925
    20. Intracerebroventricular injections of human relaxin-3 (H3) to satiated rats significantly increased food intake. PMID: 15845619
    21. NMR spectroscopy and simulated annealing calculations were used to determine the three-dimensional structure of relaxin-3 and to identify key structural differences between the human relaxins. PMID: 15956686
    22. functional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteins PMID: 15956730
    23. Results describe the solution structure of human relaxin-3. PMID: 16365033
    24. Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3. PMID: 19152634

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Insulin family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17135

    OMIM: 606855

    KEGG: hsa:117579

    STRING: 9606.ENSP00000397415

    UniGene: Hs.352155



主站蜘蛛池模板: 伊人久久大香线蕉av仙人| 美女无遮挡免费视频网站| 一卡二卡三卡视频| 一本一道vs无码中文字幕| 97成人精品区在线播放 | 国产av午夜精品一区二区三区| 最近更新中文字幕| 欧美极品少妇性运交| 无遮挡男女激烈动态图| 人妻熟妇乱又伦精品hd| 国产精品久线在线观看| 色偷拍 自怕 亚洲 10p| 少妇爆乳无码专区网站| 初尝黑人巨砲波多野结衣| 无码人妻精品一区二区在线视频| 青草伊人久久综在合线亚洲观看| 性欧美videofree高清精品| 人人妻人人澡人人爽精品日本| 亚洲a成人片在线观看| 国产成人综合在线女婷五月99播放| 中文字幕在线不卡精品视频99| 无码视频一区二区三区在线观看| 国产精品无码一区二区在线| 久久亚洲道色宗和久久 | 日日碰日日摸夜夜爽无码| 奇米777四色影视在线看| 日本最大色倩网站www| 亚洲精品色无码av试看| 无码精品一区二区三区免费视频| 免费中文熟妇在线影片| 无码内射中文字幕岛国片| 精品四虎国产在免费观看| 激情爆乳一区二区三区| 麻豆精品国产精华精华液好用吗| 国产在线欧美日韩精品一区| 正在播放国产真实露脸高清| 人妻丰满被色诱中文字幕 | 国产精品丝袜亚洲熟女| 特级做a爰片毛片免费看| 欧美怡春院一区二区三区| 成人爽a毛片免费看|