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  4. RHOF Antibody, FITC conjugated

RHOF Antibody, FITC conjugated

  • 中文名稱：
    RHOF兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA867192LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RHOF Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ARHF antibody; FLJ20247 antibody; Ras homolog gene family member F (in filopodia) antibody; Ras homolog gene family member F antibody; Rho F antibody; Rho family GTPase Rif antibody; Rho in filopodia antibody; Rho related GTP binding protein RhoF antibody; Rho-related GTP-binding protein RhoF antibody; Rhof antibody; RHOF_HUMAN antibody; RIF antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Rho-related GTP-binding protein RhoF protein (1-170AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.
  • 基因功能參考文獻(xiàn)：
    1. Rif has two separate roles in FARP1 regulation-in controlling its association with plexinA4, and in releasing active RhoA from a plexinA4/FARP1 complex. PMID: 25668492
    2. In the present review, our aim is to summarize the current information about the Rif effectors and how Rif remodels actin cytoskeleton in many aspects. [Review] PMID: 22260703
    3. The authors show that enteropathogenic Escherichia coli translocates EspH, which inactivates mammalian RhoGEFs and triggers cytotoxicity. PMID: 22251971
    4. Rif GTPase is an alternative trigger of stress-fiber formation in epithelial cells. PMID: 20233848
    5. deletion of genes RHOF in early-stage mycosis fungoides. PMID: 18663754
    6. The protein encoded by this gene causes the formation of long, actin-rich filopodia. In combination with RAC1 and CDC42 it causes additional actin rearrangments, suggesting that this protein is intimately involved in regulation of the cytoskeleton. PMID: 11084341

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  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Small GTPase superfamily, Rho family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15703

    KEGG: hsa:54509

    STRING: 9606.ENSP00000267205

    UniGene: Hs.707579



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