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RGS9BP Antibody

  • 中文名稱:
    RGS9BP兔多克隆抗體
  • 貨號(hào):
    CSB-PA765076LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunofluorescence staining of PC3 cells with CSB-PA765076LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) RGS9BP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RGS9BP
  • 別名:
    RGS9BP antibody; R9AP antibody; Regulator of G-protein signaling 9-binding protein antibody; RGS9-anchoring protein antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Regulator of G-protein signaling 9-binding protein (1-210AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,RGS9BP Antibody (CSB-PA765076LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于RGS9BP Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA765076LB01HU RGS9BP Antibody, HRP conjugated ELISA
    FITC CSB-PA765076LC01HU RGS9BP Antibody, FITC conjugated
    Biotin CSB-PA765076LD01HU RGS9BP Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:100-1:500
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation.
  • 基因功能參考文獻(xiàn):
    1. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) PMID: 19948975
    2. This is the first report describing a nonsense mutation in RGS9. PMID: 19818506
    3. five unrelated patients with recessive mutations in the genes encoding either RGS9 or R9AP who report difficulty adapting to sudden changes in luminance levels mediated by cones PMID: 14702087
    4. homozygous mutations in R9AP gene that encodes the photoreceptor GTPase accelerating protein and its anchor protein, respectively, have been identifird in patients with bradyopsia. PMID: 17698770
    5. As the light level is increased and the PDE6* concentration in the normal rises relative to that in the observer lacking RGS9-1, the temporal advantage of the latter is soon lost, leaving only the deficit due to delayed deactivation. PMID: 18318613

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  • 相關(guān)疾?。?/div>
    Prolonged electroretinal response suppression (PERRS)
  • 亞細(xì)胞定位:
    Membrane; Single-pass type IV membrane protein.
  • 蛋白家族:
    RGS7BP/RGS9BP family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30304

    OMIM: 607814

    KEGG: hsa:388531

    STRING: 9606.ENSP00000334134

    UniGene: Hs.528491



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