在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RGS6 Antibody, FITC conjugated

RGS6 Antibody, FITC conjugated

  • 中文名稱：
    RGS6兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA019658LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RGS6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RGS6
  • 別名：
    FLJ43552 antibody; G protein signaling 6 regulator antibody; GAP antibody; GTPase activating protein antibody; MGC142132 antibody; Regulator of G protein signaling 6 antibody; Regulator of G protein signalling 6 antibody; Regulator of G-protein signaling 6 antibody; RGS 6 antibody; RGS6 antibody; RGS6_HUMAN antibody; S914 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Regulator of G-protein signaling 6 protein (177-262AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity.
  • 基因功能參考文獻(xiàn)：
    1. the results suggest that HA117 regulates the development of drug resistance in CT26 cells in vitro and in vivo. PMID: 28731026
    2. study shows that HA117 potentially promotes the stem-like signature of the HL60/ATRA cell line by inhibiting by the ubiquitination and degradation of DNMT1 and by down-regulating the expression of the GGL domain of RGS6 PMID: 28665981
    3. genetic association studies on a population in Republic of Korea: Data suggest that an SNP in RGS6 (rs2239219) is closely linked to stress-induced abdominal obesity in the population studied. PMID: 28090039
    4. Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS6 in fine-tuning TRPC4 activities. PMID: 26987813
    5. Our results suggest that HA117 is a strong multidrug resistance gene. PMID: 20635168
    6. This suggests that HA117 might be an important resistance gene in pediatric solid tumors. PMID: 23619123
    7. No significant association between SNPs of RGS6 and central adiposity has been found. PMID: 26340433
    8. reduced RGS6 expression is associated with poor survival in colorectal cancer patients, suggesting that RGS6 expression may serve as an important prognostic marker PMID: 26653562
    9. these date demonstrate that RGS6 decreases in tumor tissue and may serve as a novel biomarker for outcomes in pancreatic cancer patients and be a potential therapeutic target potential therapeutic target. PMID: 25120791
    10. we found a novel mutation in RGS6, the splice-acceptor variant c.1369-1G>C that was not previously reported in congenital cataract phenotypes. PMID: 25525169
    11. genetic association studies in Hispanic-American families in Texas and Colorado: SNP in RGS6 are associated with high dietary fat intake, food preferences, and adiposity/obesity phenotype PMID: 21233807
    12. RGS6-induced apoptosis in both breast cancer cells and mouse embryonic fibroblasts does not require its GAP activity toward G proteins PMID: 21041304
    13. interacts with SCG10 and promotes neuronal differentiation; role of the G gamma subunit-like (GGL) domain of this protein PMID: 12140291
    14. Role of the RGS domain in stress-induced trafficking of RGS6 protein PMID: 12761220
    15. RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants PMID: 12761221
    16. RGS6 is the first member of the RGS protein family shown to interact with proteins involved in transcriptional regulation. PMID: 14734556

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus. Cell membrane.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10002

    OMIM: 603894

    KEGG: hsa:9628

    STRING: 9606.ENSP00000451030

    UniGene: Hs.509872



主站蜘蛛池模板： 国产精品无码无卡在线播放| 日本丰满熟妇videossex| 国产爆乳无码视频在线观看| 永久免费毛片在线播放| 高清免费精品国自产拍| 51国产偷自视频区视频| 国产精品污www在线观看| 少妇午夜啪爽嗷嗷叫视频| 日日摸夜夜摸狠狠摸婷婷| 日本日本乱码伦专区| 99精品国产成人一区二区| 国产精品免费无遮挡无码永久视频| 亚洲精品人成网线在线播放va| 国语对白做受xxxxx在| 国内嫩模私拍精品视频| 亚洲熟女乱综合一区二区| 亚洲色欲久久久久综合网| 一本久久a久久免费精品不卡| 体内射精日本视频免费看| 少妇人妻无码专区视频| 暖暖视频日本在线观看| 2021国产精品视频网站| 免费人成再在线观看视频| 欧美成人精品一区二区三区色欲| 亚洲免费观看在线视频| 午夜片神马影院福利| 成人欧美一区二区三区a片| 亚洲精品高清国产一久久| 亚洲爆乳精品无码一区二区| 久久久无码精品亚洲日韩蜜桃| 久久综合97丁香色香蕉| 欧洲免费一区二区三区视频 | 天堂√在线中文最新版| 欧美人与物videos另类| 亚洲日韩中文无码久久| 日本熟妇浓密毛毛多| 国产精品亚洲а∨无码播放不卡| 国产精品久久久久久久久久久久人四虎 | 人人妻人人澡人人爽人人精品97| 日本边添边摸边做边爱边| 99噜噜噜在线播放|