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  4. RGS22 Antibody

RGS22 Antibody

  • 中文名稱：
    RGS22兔多克隆抗體
  • 貨號：
    CSB-PA090738
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA090738(RGS22 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: CSB-PA090738(RGS22 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    RGS22
  • 別名：
    FLJ40080 antibody; FLJ75004 antibody; MGC102908 antibody; PRTD-NY2 antibody; Regulator of G-protein signaling 22 antibody; RGS22 antibody; RGS22_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human RGS22
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
  • 基因功能參考文獻：
    1. Regulator of G-protein signaling 22 (RGS22) was identified as a direct target of miR-1260b and was inhibited by miR-1260b. Knockdown of RGS22 increased proliferation of hepatocellular carcinoma cells. PMID: 29038925
    2. New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22(rs7006527). PMID: 24403052
    3. Over-expression of RGS22 in a highly metastatic esophageal cancer cell line causes decrease in cell migration and reduction in the invasive potential of the cells. PMID: 21533872
  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.
  • 組織特異性：
    Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).
  • 數據庫鏈接：

    HGNC: 24499

    OMIM: 615650

    KEGG: hsa:26166

    STRING: 9606.ENSP00000354109

    UniGene: Hs.120021



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