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RGS18 Antibody, FITC conjugated

  • 中文名稱:
    RGS18兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA019649LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RGS18
  • 別名:
    Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
  • 基因功能參考文獻:
    1. These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
    2. Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
    3. molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
    4. gene mapped to chromosome 1. PMID: 16484797
  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.
  • 數據庫鏈接:

    HGNC: 14261

    OMIM: 607192

    KEGG: hsa:64407

    STRING: 9606.ENSP00000356430

    UniGene: Hs.440890



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