在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RFX5 Antibody

RFX5 Antibody

  • 中文名稱：
    RFX5兔多克隆抗體
  • 貨號：
    CSB-PA019614GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA binding protein RFX 5 antibody; DNA binding protein RFX5 antibody; DNA-binding protein RFX5 antibody; Influences HLA class II expression antibody; Regulatory factor X 5 antibody; Regulatory factor X subunit 5 antibody; Regulatory factor X; 5 (influences HLA class II expression) antibody; RFX 5 antibody; RFX5 antibody; Rfx5 protein antibody; RFX5_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human RFX5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
  • 基因功能參考文獻：
    1. RFX5 acts as a direct positive transcriptional regulator of TPP1 in hepatocellular carcinoma. PMID: 27840983
    2. Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression. PMID: 23911394
    3. these data have identified as novel pathway whereby SIRT1 maintains COL1A2 synthesis in SMCs by modulating RFX5 activity. PMID: 23079621
    4. RFXAP(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple. PMID: 20732328
    5. interaction at COL1A2 start site and transcription repression PMID: 11986307
    6. The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function. PMID: 12368908
    7. RFX5 binds to the collagen transcription start site and represses collagen gene expression PMID: 12968017
    8. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression. PMID: 15210800
    9. RFXAP and RFXB have roles in relieving autoinhibition of RFX5 PMID: 18723135
    10. TSA treatment enhances the association of CIITA with the transcription factor RFX5, which ameliorates the down-regulation of CIITA recruitment to target promoters by HDAC2. PMID: 19041327

    顯示更多

    收起更多

  • 相關疾病：
    Bare lymphocyte syndrome 2 (BLS2)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    RFX family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 9986

    OMIM: 209920

    KEGG: hsa:5993

    STRING: 9606.ENSP00000290524

    UniGene: Hs.632472



主站蜘蛛池模板： 国产露脸150部国语对白| 国产激情综合在线看| 欧美精欧美乱码一二三四区 | 国产精品久久人妻无码网站一区| 最近免费中文字幕大全免费版视频| 亚洲另类欧美小说图片区| 久久99热只有频精品8| 国产精品人人做人人爽人人添| 日韩成人一区二区三区在线观看| 亚洲中文字幕丝祙制服| 国产精品福利2020久久| 大地资源中文在线观看官网第二页| 人妻体内射精一区二区| 四虎影视精品永久在线观看| 亚洲狠狠爱综合影院网页| 国产午夜精品一区二区三区| 精品国产av色一区二区深夜久久| 麻豆蜜桃av蜜臀av色欲av| 国产免费不卡av在线播放| 又色又爽又黄的视频网站 | 国产激情久久久久影院小草| 亚洲日韩国产中文其他| 人妻一本久道久久综合久久鬼色| 中文字幕在线观看亚洲日韩| 免费看无码自慰一区二区| 亚洲精品一卡2卡三卡4卡 | 亚洲美女国产精品久久久久久久久| h无码精品3d动漫在线观看| 国产精品久久久久久久免费看| 潮喷失禁大喷水无码| 午夜性色福利在线视频福利| 色无码av在线播放| 娇妻玩4p被三个男人伺候电影| 无码欧美黑人xxx一区二区三区| 久久国产超碰女女av| 欧美午夜一区二区福利视频| 国产精品久久久国产盗摄| 成人污污污www网站免费| 色欲色香天天天综合vvv| 浮妇高潮喷白浆视频| a毛片免费全部播放自慰|