在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RFX5 Antibody

RFX5 Antibody

  • 中文名稱：
    RFX5兔多克隆抗體
  • 貨號：
    CSB-PA019614GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA binding protein RFX 5 antibody; DNA binding protein RFX5 antibody; DNA-binding protein RFX5 antibody; Influences HLA class II expression antibody; Regulatory factor X 5 antibody; Regulatory factor X subunit 5 antibody; Regulatory factor X; 5 (influences HLA class II expression) antibody; RFX 5 antibody; RFX5 antibody; Rfx5 protein antibody; RFX5_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human RFX5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
  • 基因功能參考文獻：
    1. RFX5 acts as a direct positive transcriptional regulator of TPP1 in hepatocellular carcinoma. PMID: 27840983
    2. Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression. PMID: 23911394
    3. these data have identified as novel pathway whereby SIRT1 maintains COL1A2 synthesis in SMCs by modulating RFX5 activity. PMID: 23079621
    4. RFXAP(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple. PMID: 20732328
    5. interaction at COL1A2 start site and transcription repression PMID: 11986307
    6. The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function. PMID: 12368908
    7. RFX5 binds to the collagen transcription start site and represses collagen gene expression PMID: 12968017
    8. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression. PMID: 15210800
    9. RFXAP and RFXB have roles in relieving autoinhibition of RFX5 PMID: 18723135
    10. TSA treatment enhances the association of CIITA with the transcription factor RFX5, which ameliorates the down-regulation of CIITA recruitment to target promoters by HDAC2. PMID: 19041327

    顯示更多

    收起更多

  • 相關疾病：
    Bare lymphocyte syndrome 2 (BLS2)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    RFX family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 9986

    OMIM: 209920

    KEGG: hsa:5993

    STRING: 9606.ENSP00000290524

    UniGene: Hs.632472



主站蜘蛛池模板： 天天躁日日躁aaaxxⅹ| 嫩b人妻精品一区二区三区| 亚洲精品第一国产综合精品| 日韩a片无码一区二区三区电影 | 爱情岛论坛网亚洲品质| 日本添下边视频全过程| 色先锋资源久久综合5566| 欧美日韩人成视频在线播放| 性开放的欧美大片| 日韩精品成人无码专区免费| 日产精品一区2区卡四卡二卡| 亚洲中文字幕无码卡通动漫野外| 精品人妻无码区二区三区 | 忘忧草影院在线www韩国日本| 无码熟妇人妻av在线电影| 色婷婷日日躁夜夜躁| 啊轻点内射在线视频| 成人乱码一区二区三区四区| 国产成人拍精品视频午夜网站 | 在线成人a毛片免费播放| 成人网站免费高清视频在线观看| 毛片内射久久久一区| 性按摩xxxx在线观看| 翘臀后进少妇大白嫩屁股| 色综合视频一区二区三区44 | 狠狠躁18三区二区一区ai明星| 少妇无码一区二区三区| 免费全部高h视频无码| 最新在线精品国自产拍视频| 国产精品美女一区二区三区 | 夜夜澡人摸人人添人人看| 国产亚洲精品在av| julia无码中文字幕一区| 国产精品白丝av在线观看播放| 麻豆成人久久精品综合网址| 欧美乱妇高清无乱码| 亚洲中文字幕精品久久| 亚洲最大无码中文字幕网站 | 一本加勒比hezyo无码资源网| 人妻少妇精品视频无码专区| 久久精品aⅴ无码中文字字幕|