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  4. RERG Antibody

RERG Antibody

  • 中文名稱：
    RERG兔多克隆抗體
  • 貨號：
    CSB-PA019569GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RERG
  • 別名：
    MGC15754 antibody; RAS like estrogen regulated growth inhibitor antibody; Ras related and estrogen regulated growth inhibitor antibody; Ras-related and estrogen-regulated growth inhibitor antibody; Rerg antibody; RERG_HUMAN antibody; Weakly similar to N ras protein [H.sapiens] antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RERG
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
  • 基因功能參考文獻(xiàn)：
    1. this study shows that miR-382-5p expression is negatively correlated with RERG expression, and functions as an independent oncomiR for the higher incidence and poorer prognosis of breast cancer PMID: 27705918
    2. Estradiol estrogen receptor-beta and PGE2 integrate at RERG, leading to increased endometriotic cell proliferation. PMID: 24992181
    3. Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. PMID: 21270509
    4. Loss of RERG expression is associated with breast cancer and distant metastasis. PMID: 20697807
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Small GTPase superfamily, Ras family
  • 組織特異性：
    Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15980

    OMIM: 612664

    KEGG: hsa:85004

    STRING: 9606.ENSP00000256953

    UniGene: Hs.199487



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