在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RER1 Antibody, Biotin conjugated

RER1 Antibody, Biotin conjugated

  • 中文名稱：
    RER1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA019567LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RER1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RER1
  • 別名：
    RER1; Protein RER1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein RER1 protein (85-139AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
  • 基因功能參考文獻：
    1. RER1 is a novel and potential important mediator of elevated alphaSyn levels PMID: 28877262
    2. Rer1p regulates the ER retention of immature or misfolded rhodopsin and modulates its intracellular trafficking through the early secretory pathway. PMID: 25096327
    3. Charcot-Marie-Tooth disease-related PMP22 is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1-mediated endoplasmic reticulum-associated degradation system. PMID: 25385046
    4. Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch signaling as well as reducing Foxj1a expression. PMID: 23479743
    5. Synoviolin up-regulates amyloid beta production by targeting a negative regulator of gamma-secretase, Rer1, for degradation. PMID: 23129766
    6. RER1 modulates amyloid-beta production by altering trafficking of gamma-secretase and amyloid precursor protein. PMID: 23043097
    7. Downregulation of Rer1 leads to increased surface localization of Pen2, whereas overexpression of Rer1 stabilizes unassembled Pen2. Rer1 is the first identified interaction partner of mammalian transmembrane-based retention/retrieval signals. PMID: 17668005

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    RER1 family
  • 數據庫鏈接：

    HGNC: 30309

    KEGG: hsa:11079

    STRING: 9606.ENSP00000302088

    UniGene: Hs.525527



主站蜘蛛池模板： 天堂资源中文| 久久久久久成人综合网| 亚洲成亚洲成网| 无码人妻丰满熟妇区bbbbxxxx| 好吊妞视频这里有精品| 国产青草视频在线观看| 国产精品色拉拉| 国产亚洲精品综合一区| 久久久久波多野结衣高潮| 久久av无码αv高潮αv喷吹| 国产精品成人a区在线观看| 高潮潮喷奶水飞溅视频无码| 亚洲色一色噜一噜噜噜| 麻豆av一区二区三区久久| 精品无码久久久久国产手机版| 亚洲欧美成人综合图区| 久久久久久无码av成人影院| 久久久久久久久久久久| 寂寞骚妇被后入式爆草抓爆| 一个人看免费视频www| 被拉到野外强要好爽黑人| 中文字幕在线播放| 少妇下蹲露大唇无遮挡| 日本亚洲欧美在线视观看| 夜夜爱夜鲁夜鲁很鲁| 日本丰满熟妇videossex8k| 精品国产一区二区三区四区在线看 | 国产9色在线 | 日韩| 成人无码www在线看免费| 日日日日做夜夜夜夜做无码| 西西人体做爰大胆性自慰| 人妻体内射精一区二区三区 | 人妻无码中文久久久久专区| 强开小婷嫩苞又嫩又紧视频韩国| 日韩精品无码免费一区二区三区| 国产精品无码久久四虎| 色欲国产麻豆一精品一av一免费 | 亚洲另类自拍丝袜第五页| 国产精品调教视频一区| 99久久婷婷国产综合精品青草免费 | 国产精品对白刺激久久久|