REEP6 Antibody
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中文名稱：REEP6兔多克隆抗體
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貨號(hào)：CSB-PA019545GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：REEP6; C19orf32; DP1L1; Receptor expression-enhancing protein 6; Polyposis locus protein 1-like 1
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human REEP6
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis. May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane.
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基因功能參考文獻(xiàn)：
- Depletion of receptor accessory proteins REEP5 and REEP6 causes a decrease in CXC Chemokine Receptor 1 (CXCR1) signaling. PMID: 27966653
- study implicates REEP6 in retinal homeostasis and highlights a pathway previously uncharacterized in retinal dystrophy PMID: 27889058
- DP1L1 polymorphisms are associated with colon cancer and IBD. This indicates that DP1L1 plays a functional role in these conditions. Thus DP1L1 may be a diagnostic and therapeutic target for colon cancer and IBD. PMID: 19924442
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相關(guān)疾病：Retinitis pigmentosa 77 (RP77)
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亞細(xì)胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein.
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蛋白家族：DP1 family
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組織特異性：Expressed in circumvallate papillae and testis. Expressed in the retina. Isoform 1 is predominantly present in mature optic cups. Isoform 1 expression is confined to the cell body and inner segment of developing rod photoreceptor cells.
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數(shù)據(jù)庫(kù)鏈接：
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