在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. REC8 Antibody

REC8 Antibody

  • 中文名稱：
    REC8兔多克隆抗體
  • 貨號：
    CSB-PA019535GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    REC8
  • 別名：
    Cohesin Rec8p antibody; Human homolog of rad21 S. pombe antibody; Meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family antibody; Meiotic recombination protein REC8 homolog antibody; Meiotic recombination protein REC8-like 1 antibody; rec8 antibody; REC8 homolog (yeast) antibody; REC8 like 1 antibody; REC8_HUMAN antibody; Rec8p antibody; Recombination and sister chromatid cohesion protein homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human REC8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
  • 基因功能參考文獻：
    1. we determined that REC8 interacted with EGR1, and inhibited EMT in gastric cancer cells. We thus propose further studies of the pathways associated with REC8 and EGR1 to potentially find novel targets in the treatment for gastric cancer. PMID: 29393474
    2. Study confirmed that REC8 was downregulated in gastric neoplasm, especially in the EBV-associated subtype, via promoter methylation. PMID: 27212034
    3. REC8 being a novel major bona fide tumor suppressor gene and a robust epigenetic target of the PI3K pathway. Aberrant inactivation of REC8 through hypermethylation by the PI3K pathway may represent an important mechanism mediating the oncogenic functions of the PI3K pathway PMID: 26472282
    4. Indicate that polymorphisms of the Rec 8 gene are not a common cause of severe male factor infertility. PMID: 18570052
    5. Data show that REC8 is constitutively expressed in tumour cells, along with SGOL1 and SGOL2, and that REC8 becomes modified after irradiation. PMID: 19463812
    6. The mouse ortholog of REC8L1 is required for proper synapsis of homologous chromosomes during meiosis PMID: 15935783

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome. Chromosome, centromere.
  • 蛋白家族：
    Rad21 family
  • 組織特異性：
    Expressed in testis and thymus. Expressed in the B-cell lines WI-L2-NS and Namalwa (at protein level).
  • 數據庫鏈接：

    HGNC: 16879

    OMIM: 608193

    KEGG: hsa:9985

    STRING: 9606.ENSP00000308699

    UniGene: Hs.419259



主站蜘蛛池模板： 国产末成年女av片一区二区| 国产成人8x人网站视频| 亚洲国产老鸭窝一区二区三区| 日本国产制服丝袜一区| 亚洲婷婷综合色高清在线| 好爽…又高潮了免费毛片| 综合无码成人aⅴ视频在线观看 | av狠狠色超碰丁香婷婷综合久久| 久久久一本精品99久久精品66直播| 天干夜天天夜天干天2004年| 夜夜影院未满十八勿进| 日韩av无码成人无码免费| 性一交一乱一伦一| 精品一区二区三区四区五区六区| 亚裔大战黑人老外av| 女人被男人桶30分钟无遮挡动态图 | 性久久久久久| 国产精品自产拍在线18禁| 在线观看国产丝袜控网站 | 2022一本久道久久综合狂躁| 人人插人人插人人爽| 亚洲va久久久噜噜噜久久天堂| 日韩av无码一区二区三区不卡毛片| 国产熟睡乱子伦午夜视频麻豆| 久久亚洲精品11p| 狠狠色丁香婷婷综合尤物| 久久66热人妻偷产精品9| 久久久精品日本一区二区三区| 欧美牲交a欧美在线| 77777亚洲午夜久久多喷| 亚洲最大av网站在线观看 | 扒开女人内裤猛进猛出免费视频| 欧美人与动牲交zooz乌克兰| 综合图片亚洲综合网站| 日韩精品亚洲人旧成在线| 大地资源在线观看官网第三页| 日韩精品无码一区二区三区| 国产卡二卡三卡四卡免费网址| 中文字幕欧美亚州视频免费| 亚洲中文字幕无码爆乳| 国产精品一区二区香蕉|