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RCBTB1 Antibody

  • 中文名稱:
    RCBTB1兔多克隆抗體
  • 貨號:
    CSB-PA019503GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    RCBTB1
  • 別名:
    Chronic lymphocytic leukemia deletion region gene 7 protein antibody; CLL deletion region gene 7 protein antibody; CLLL7 antibody; CLLL7 protein antibody; E4.5 antibody; GDP/GTP exchange factor (GEF) like protein antibody; GLP antibody; Guanine nucleotide exchange factor antibody; Hypothetical protein FLJ39335 antibody; RCBT1_HUMAN antibody; Rcbtb1 antibody; RCC1 and BTB domain-containing protein 1 antibody; Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antibody; Regulator of chromosome condensation and BTB domain-containing protein 1 antibody; RP11-185C18.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RCBTB1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in cell cycle regulation by chromatin remodeling.
  • 基因功能參考文獻:
    1. Data indicate RNA Binding Protein with Multiple Splicing (RBPMS), Regulator of Chromosome Condensation and POZ Domain Containing Protein 1 (RCBTB1), and Zinc Finger protein 608 (ZNF608) as miR-21-3p target genes. PMID: 27166999
    2. study puts forward mutations in RCBTB1 as a cause of autosomal-recessive non-syndromic and syndromic inherited retinal dystrophies; data support a role for impaired ubiquitination in the pathogenetic mechanism of RCBTB1 mutations PMID: 27486781
    3. Results identified RCBTB1 as a gene associated with vitreoretinopathy and found that it plays a role in retinal angiogenesis through Norrin-induced beta-catenin signaling. PMID: 26908610
    4. Study identifies RCBTB1 as a modifier of the smoking effect on carotid intima-media thickness. PMID: 24202307
    5. Data show that the biological actions of Clld7 are consistent with those of a tumor suppressor. PMID: 20926398
    6. E4.5 gene, which maps at chromosome band 13q14.3, encodes for a 4 kb mRNA expressed in various tissues and has an open reading frame of 531 amino acids. It has a potential role in the pathogenesis of chronic lymphocytic leukemia [E4.5] PMID: 14565662

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  • 相關疾病:
    Retinal dystrophy with or without extraocular anomalies (RDEOA)
  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Ubiquitously expressed. In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level).
  • 數據庫鏈接:

    HGNC: 18243

    OMIM: 607867

    KEGG: hsa:55213

    STRING: 9606.ENSP00000258646

    UniGene: Hs.508021



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