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  4. RBM28 Antibody

RBM28 Antibody

  • 中文名稱：
    RBM28兔多克隆抗體
  • 貨號：
    CSB-PA019419GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    2810480G15Rik antibody; FLJ10377 antibody; RBM 28 antibody; RBM28 antibody; RBM28_HUMAN antibody; RNA binding motif protein 28 antibody; RNA binding protein 28 antibody; RNA-binding motif protein 28 antibody; RNA-binding protein 28 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RBM28
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Nucleolar component of the spliceosomal ribonucleoprotein complexes.
  • 基因功能參考文獻：
    1. The authors conclude that the ANE syndrome mutation generates defective RBM28 protein folding which abrogates protein-protein interactions and causes faulty pre-large subunit rRNA processing, thus revealing one aspect of the molecular basis of this human disease. PMID: 27077951
    2. RBM28 controls the expression of miR-203. RBM28 contributes to hair follicle growth regulation through modulation of miR-203 and p63 activity. PMID: 25939713
    3. RBM28 gene defects should be added to the growing list of gene defects associated with syndromic combined anterior pituitary hormone deficiency. PMID: 20231366
    4. RBM28 is a common nucleolar component of the spliceosomal ribonucleoprotein complexes, possibly coordinating their transition through the nucleolus PMID: 17081119
    5. A loss-of-function mutation is found in RBM28, encoding a nucleolar protein in patients with alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome). PMID: 18439547

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  • 相關疾病：
    Alopecia, neurologic defects, and endocrinopathy syndrome (ANES)
  • 亞細胞定位：
    Nucleus, nucleolus.
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 21863

    OMIM: 612074

    KEGG: hsa:55131

    STRING: 9606.ENSP00000223073

    UniGene: Hs.274263



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