在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RBFOX3 Antibody, FITC conjugated

  • 中文名稱:
    RBFOX3兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA407385LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RBFOX3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RBFOX3
  • 別名:
    FLJ56884 antibody; FLJ58356 antibody; Fox-1 homolog C antibody; fox1 homolog C antibody; Fox3 antibody; FOX3NeuN antibody; hexaribonucleotide binding protein 3 antibody; HRNBP3 antibody; NEUN antibody; neuronal nuclei antibody; Rbfox3 antibody; RFOX3_HUMAN antibody; RNA binding protein fox-1 homolog 3 antibody; RNA binding protein, fox 1 homolog (C. elegans) 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human RNA binding protein fox-1 homolog 3 protein (1-101AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
  • 基因功能參考文獻:
    1. RBFOX3 knockdown synergized with 5-FU to inhibit the growth and invasion of HCC cells through PI3K/AKT and epithelial-mesenchymal transition (EMT) signaling, and promote apoptosis by activating the cytochrome-c/caspase signaling pathway. PMID: 29689552
    2. In human lung tissue, Claudin-1 is higher in RBFOX3-positive cells than in RBFOX3-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 are increased by RBFOX3. PMID: 28126724
    3. SNPs (rs9900428, rs9907432 and rs7211029) in RBFOX3 associate with sleep latency. PMID: 27142678
    4. this study show that TGF-beta-induced RBFOX3 inhibition plays an important role in epithelial-mesenchymal transition and lung cancer progression PMID: 27432190
    5. NeuN was recently eventually identified as an epitope of Rbfox3. NeuN is highly conserved among species and is stably expressed during specific stages of development. NeuN has been considered to be a reliable marker of mature neurons, however, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and states. Review. PMID: 25680637
    6. RNA splicing occurs in the nucleus hence, the altered localization of RbFox3 to the cytoplasm may lead to the downregulation of neuronal gene expression. PMID: 24215932
    7. High NeuN levels are associated with supratentorial ependymomas. PMID: 23371454
    8. NeuN immunocytochemical reaction in neurons of human substantia nigra was expressed much weaker than in the nucleus rubrum neurons located in the same sections. PMID: 23898728
    9. NeuN (neuronal nuclei) is a neuron-specific nuclear protein identified by anti-NeuN antibody, and widely used as the postmitotic neuron marker. NeuN is identified as the Fox-3 gene product by mass spectrometry, immunoblotting, RNAi, and immunostaining. PMID: 19713214

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 27097

    OMIM: 616999

    KEGG: hsa:146713

    STRING: 9606.ENSP00000393262

    UniGene: Hs.135229



主站蜘蛛池模板: 成年美女黄网站色大免费视频 | 正在播放重口老熟女露脸| 一本色道av久久精品+网站| 亚洲人成77在线播放网站| 午夜爽爽爽男女免费观看麻豆国产| 国产作爱视频免费播放| 国产精品涩涩涩视频网站| 国产老妇伦国产熟女老妇视频| 国产亚洲视频在线观看播放| 久久精品国产只有精品2020| 中文字幕亚洲一区二区三区| 40岁成熟女人牲交片20分钟| 无码人妻丰满熟妇区五十路百度| 色欲色香天天天综合无码| 中文字幕漂亮人妻熟睡中被公侵犯| 曰批全过程免费视频在线观看无码| 国产女人18毛片水真多1| 综合三区后入内射国产馆| 综合精品欧美日韩国产在线| 亚洲欧美日韩在线一区| 精品福利一区二区三区免费视频| 亚洲人成影院在线无码按摩店| 欧美亚洲国产手机在线有码| 亚洲综合激情五月丁香六月| 精品人人妻人人澡人人爽牛牛| 亚洲国产午夜精品理论片在线播放| 国产精品国产三级国产an| 日韩在线 | 中文| 男女啪啪进出阳道猛进| 性生交大全免费看| 精品亚洲欧美自拍| 国产美女精品视频线播放| 人妻熟女一区| 国产无线乱码一区二三区| 中文 在线 日韩 亚洲 欧美| 日韩放荡少妇无码视频| 国产精品美女久久久久久久久| 欧美乱大交xxxxx潮喷| 亚洲制服丝袜自拍中文字幕| 久久天天躁狠狠躁夜夜2020一| 久久久久久久无码高潮|