在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RBFOX3 Antibody, FITC conjugated

  • 中文名稱:
    RBFOX3兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA407385LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RBFOX3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RBFOX3
  • 別名:
    FLJ56884 antibody; FLJ58356 antibody; Fox-1 homolog C antibody; fox1 homolog C antibody; Fox3 antibody; FOX3NeuN antibody; hexaribonucleotide binding protein 3 antibody; HRNBP3 antibody; NEUN antibody; neuronal nuclei antibody; Rbfox3 antibody; RFOX3_HUMAN antibody; RNA binding protein fox-1 homolog 3 antibody; RNA binding protein, fox 1 homolog (C. elegans) 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human RNA binding protein fox-1 homolog 3 protein (1-101AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
  • 基因功能參考文獻:
    1. RBFOX3 knockdown synergized with 5-FU to inhibit the growth and invasion of HCC cells through PI3K/AKT and epithelial-mesenchymal transition (EMT) signaling, and promote apoptosis by activating the cytochrome-c/caspase signaling pathway. PMID: 29689552
    2. In human lung tissue, Claudin-1 is higher in RBFOX3-positive cells than in RBFOX3-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 are increased by RBFOX3. PMID: 28126724
    3. SNPs (rs9900428, rs9907432 and rs7211029) in RBFOX3 associate with sleep latency. PMID: 27142678
    4. this study show that TGF-beta-induced RBFOX3 inhibition plays an important role in epithelial-mesenchymal transition and lung cancer progression PMID: 27432190
    5. NeuN was recently eventually identified as an epitope of Rbfox3. NeuN is highly conserved among species and is stably expressed during specific stages of development. NeuN has been considered to be a reliable marker of mature neurons, however, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and states. Review. PMID: 25680637
    6. RNA splicing occurs in the nucleus hence, the altered localization of RbFox3 to the cytoplasm may lead to the downregulation of neuronal gene expression. PMID: 24215932
    7. High NeuN levels are associated with supratentorial ependymomas. PMID: 23371454
    8. NeuN immunocytochemical reaction in neurons of human substantia nigra was expressed much weaker than in the nucleus rubrum neurons located in the same sections. PMID: 23898728
    9. NeuN (neuronal nuclei) is a neuron-specific nuclear protein identified by anti-NeuN antibody, and widely used as the postmitotic neuron marker. NeuN is identified as the Fox-3 gene product by mass spectrometry, immunoblotting, RNAi, and immunostaining. PMID: 19713214

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 27097

    OMIM: 616999

    KEGG: hsa:146713

    STRING: 9606.ENSP00000393262

    UniGene: Hs.135229



主站蜘蛛池模板: 中文字幕无码精品亚洲资源网| 国产精品久久精品第一页| 中文成人无码精品久久久动漫| 国产成人夜色高潮福利影视| 久99久热只有精品国产15| 秋霞影院午夜伦a片欧美| 性做久久久久久免费观看 | 猫咪www免费人成人入口| 夜夜未满十八勿进的爽爽影院| 亚洲女人自熨在线视频| 琪琪秋霞午夜av影视在线| 国色天香成人一区二区| 在线精品自偷自拍无码中文| 欧美成人一区二免费视频软件| 精品人妻少妇一区二区三区不卡| 亚洲一区在线日韩在线秋葵| 国产精品_九九99久久精品| 99久久精品费精品国产一区二| 国产无遮挡又黄又爽免费视频| 国产午夜精品一区二区| 一本久久综合亚洲鲁鲁五月天| av天堂中av世界中文在线播放| 国产成人av在线免播放观看 | 精产国品一二三产品麻豆| 丰满少妇人妻无码| 又粗又大内射免费视频小说| 人妻夜夜爽天天爽三区麻豆av网站 | 人妻中出受孕 中文字幕在线| 级r片内射在线视频播放| 琪琪电影午夜理论片八戒八戒| 52熟女露脸国语对白视频| 中日产幕无线码一区| 久久精品一区二区三区中文字幕| 波多野42部无码喷潮在线| 色欲人妻aaaaaa无码| 国产激情高中生呻吟视频 | 国产美女精品视频线免费播放软件 | 国产精品久久久久电影网| 成人乱码一区二区三区av| 天堂网在线.www天堂在线资源| 偷偷要色偷偷中文无码|