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Your Good Partner in Biology Research

RBAK Antibody

  • 中文名稱:
    RBAK兔多克隆抗體
  • 貨號:
    CSB-PA003952
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HepG2 cells using RBAK Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    RBAK
  • 別名:
    hRBaK antibody; Hypothetical protein RBAK antibody; RB associated KRAB zinc finger antibody; RB-associated KRAB repressor antibody; RB-associated KRAB zinc finger protein antibody; RBAK antibody; RBAK_HUMAN antibody; Zinc finger protein 769 antibody; ZNF 769 antibody; ZNF769 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human RBAK.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May repress E2F-dependent transcription. May promote AR-dependent transcription.
  • 基因功能參考文獻:
    1. Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states. PMID: 20466629
    2. RBaK interacts with the androgen receptor and increases its transcriptional activity. PMID: 14664718
    3. study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II PMID: 17121540
    4. The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied. PMID: 18307725
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Krueppel C2H2-type zinc-finger protein family
  • 組織特異性:
    Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
  • 數據庫鏈接:

    HGNC: 17680

    OMIM: 608191

    KEGG: hsa:57786

    STRING: 9606.ENSP00000275423

    UniGene: Hs.396178



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