在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RASGRP3 Antibody

  • 中文名稱:
    RASGRP3兔多克隆抗體
  • 貨號:
    CSB-PA019364GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Calcium and DAG-regulated guanine nucleotide exchange factor III antibody; Grp3 antibody; GRP3_HUMAN antibody; Guanine nucleotide exchange factor for Rap1 antibody; Kiaa0846 antibody; RAS guanyl releasing protein 3 (calcium and DAG regulated) antibody; RAS guanyl releasing protein 3 calcium and DAG regualated guanine nucleotide exchange factor iii antibody; Ras guanyl-releasing protein 3 antibody; RASGRP3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RASGRP3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
  • 基因功能參考文獻:
    1. In conclusion, these findings provide a new insight into the upregulation of RasGRP3 involved in Notch pathway activation in the development of esophageal squamous cell carcinoma , especially under nutrient deprivation. PMID: 29048643
    2. these data show that RasGRP3 exerts its oncogenic effect in papillary thyroid cancer through Akt-mediated MDM2 activation. PMID: 28864115
    3. RasGRP3 mediates ERK MAPK pathway activation in GNAQ mutant uveal melanoma. PMID: 28486107
    4. Knockdown of RasGRP3 inhibited proliferation in prostate neoplasms. PMID: 24418912
    5. Ras activator RasGRP3 may have a role in the pathological behavior of breast cancer cells and may constitute a therapeutic target for human breast cancer. PMID: 24779681
    6. The identification of the role of RasGRP3 in melanoma highlights its importance, as a Ras activator, in the phosphoinositide signaling pathway in human melanoma. PMID: 21602881
    7. Significant associations were found for the single nucleotide polymorphism rs13385731 of RasGRP3 with malar rash, discoid rash, and antinuclear antibody in patients with systemic lupus erythematosus PMID: 20516000
    8. RasGRP3 contributes to the malignant phenotype of prostate cancer cells and may constitute a novel therapeutic target for human prostate cancer. PMID: 20876802
    9. A vascular gene trap screen defines RASGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. PMID: 15572660
    10. studies support the hypothesis that RasGRP phosphorylation by PKC is a mechanism that integrates DAG signaling systems in T and B cells PMID: 15657177
    11. dynein light chain 1 represents a novel anchoring protein for RasGRP3 that may regulate subcellular localization of the exchange factor PMID: 17012239

    顯示更多

    收起更多

  • 蛋白家族:
    RASGRP family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14545

    OMIM: 609531

    KEGG: hsa:25780

    STRING: 9606.ENSP00000384192

    UniGene: Hs.143674



主站蜘蛛池模板: 国产女人好紧好爽| 无码人妻一区二区三区四区av| 波多野结衣初尝黑人| 国产免费看插插插视频| √天堂资源地址在线官网| 极品国产主播粉嫩在线| 激情射精爽到偷偷c视频无码| 无码国产69精品久久久孕妇| 国产精品女同一区二区| 2018亚洲а∨天堂| 亚洲色成人一区二区三区| 中文字幕人成无码人妻综合社区| 青娱乐极品视觉盛宴国产视频| 亚洲在av极品无码天堂手机版| 国产精品55夜色66夜色| 人人妻人人澡人人爽人人精品 | 无码人妻精品中文字幕| 亚洲韩国日本高清一区| 800av凹凸视频在线观看| 久久精品人妻无码一区二区三区| 丰满人妻一区二区三区无码av | 制服丝袜有码中文字幕在线| 亚洲v天堂v手机在线| 亚洲色成人网一二三区 | 美女扒开奶罩露出奶头视频网站| 乱人伦中文无码视频| 中文国产成人精品久久不卡| 亚洲熟妇无码久久精品| 国产最新av在线播放不卡| 99久久国产综合精品成人影院| 久久久久噜噜噜亚洲熟女综合| 亚洲最大av一区二区三区| 女女女女女裸体开bbb| 中文字幕丰满乱子伦无码专区| 高清粉嫩无套内谢国语播放| 久久这里只有是精品23| 人妻熟女一区二区aⅴ千叶宁真 | 无码人妻aⅴ一区二区三区69岛| 少妇愉情理伦片高潮日本| 日本亚洲欧美日韩国产ay | 久久国产欧美成人网站|