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  4. RASGEF1B Antibody, Biotin conjugated

RASGEF1B Antibody, Biotin conjugated

  • 中文名稱：
    RASGEF1B兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA610807LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RASGEF1B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RASGEF1B
  • 別名：
    FLJ31695 antibody; GPI gamma-4 antibody; GPIG4 antibody; MGC46251 antibody; Ras-GEF domain-containing family member 1B antibody; RasGEF domain family member 1B antibody; RASGEF1B antibody; RGF1B_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ras-GEF domain-containing family member 1B protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
  • 基因功能參考文獻：
    1. We show that knockdown of the expression of mcircRasGEF1B reduces LPS-induced ICAM-1 expression. Additionally, we demonstrate that mcircRasGEF1B regulates the stability of mature ICAM-1 mRNAs. PMID: 27362560
    2. As an addition to PRKG2 and RASGEFIB genes, we propose to include BMP3 gene as the principal determinant of the observed common phenotype. PMID: 22303795
    3. Mutation of the Ser39 in Rap1 changed the specificity and allowed the nucleotide exchange of Rap1(S39F) to be stimulated by RasGEF1B PMID: 19645719
  • 亞細胞定位：
    Early endosome. Late endosome. Midbody.
  • 數據庫鏈接：

    HGNC: 24881

    OMIM: 614532

    KEGG: hsa:153020

    STRING: 9606.ENSP00000264400

    UniGene: Hs.591696



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