在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RASD2 Antibody
  • 中文名稱：
    RASD2兔多克隆抗體
  • 貨號：
    CSB-PA249540
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA249540(RASD2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA249540(RASD2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 cell and mouse kidney tissue, Primary antibody: CSB-PA249540(RASD2 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RASD2
  • 別名：
    GTP binding protein Rhes antibody; GTP-binding protein Rhes antibody; MGC:4834 antibody; OTTHUMP00000197925 antibody; Ras homolog enriched in striatum antibody; RASD 2 antibody; RASD family member 2 antibody; RASD2 antibody; Rhes antibody; RHES_HUMAN antibody; TEM 2 antibody; TEM2 antibody; Tumor endothelial marker 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Full length fusion protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
  • 基因功能參考文獻(xiàn)：
    1. Study demonstrated that variation in the gene coding for RASD2 (rs6518956) affects in vivo prefrontal and striatal phenotypes in healthy human subjects that are relevant to schizophrenia PMID: 26228524
    2. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion PMID: 26190541
    3. Findings reveal that ras homolog enriched in striatum is localized also in striatal cholinergic interneurons and, most importantly, lack of this G-protein, significantly alters dopamine D2 receptor modulation of striatal cholinergic excitability. PMID: 25818655
    4. Rhes is reduced in the brains of Huntington's disease patients. PMID: 25556834
    5. The findings of this study suggested that Rhes may play a crucial role in striatal iron homeostasis. PMID: 23999124
    6. Rhes robustly binds the autophagy regulator Beclin-1, decreasing its inhibitory interaction with Bcl-2 independent of JNK-1 signaling. PMID: 24324270
    7. The sequestering of Rhes through its binding to mutant huntingtin may decrease the ability of Rhes to perform vital physiological functions in the striatum neurons of Huntington disease patients. (Review) PMID: 23583659
    8. Rhes is an imidazoline-regulated transcript in pancreatic beta-cells PMID: 16945334
    9. Rhes can interfere with the functional activity of wt and mutated TSHr and with the respective hormone-stimulated cAMP production of FSHr and LHr. PMID: 17556863
    10. The genes RASD2 might be vulnerability genes for neuropsychologically defined subgroups of schizophrenic patients. PMID: 18571626
    11. Binding to the Gbeta subunits involves the cationic regions of AGS1 and Rhes, and Data used Rhes-AGS1 chimeras to show that their different cationic regions determine the Gbeta-specificity of the interactions. PMID: 19255495

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor.
  • 蛋白家族：
    Small GTPase superfamily, RasD family
  • 組織特異性：
    Pancreatic endocrine cells (islets of Langerhans).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18229

    OMIM: 612842

    KEGG: hsa:23551

    STRING: 9606.ENSP00000216127

    UniGene: Hs.474711



主站蜘蛛池模板： 亚洲成av人片在线观看无码不卡| 男女久久久国产一区二区三区| 国产午夜不卡片免费视频| 欧美又黄又大又爽a片三年片| 扒开女人内裤猛进猛出免费视频| 老子午夜精品无码不卡| 日本公与熄乱理在线播放| 成人亚洲一区无码久久| 亚洲精品aa片在线观看国产| 午夜不卡av免费| 少妇高潮喷潮久久久影院| 99视频精品国产免费观看| 天堂网www在线资源最新版| 欧美日韩精品一区二区在线视频| 美女视频黄频大全免费| 国内精品伊人久久久久影院麻豆| 久久777国产线看观看精品 | 看国产一毛片在线看手机看| 2020精品国产a不卡片| 亚洲国产精品一区二区www| 国产免费久久精品99久久 | 亚洲红杏成在人线免费视频| 国产精品白丝av网站| 国产高清乱理伦片中文小说| 国产精品美女久久久久久久久| 日本真人做爰免费的视频| 亚洲精品无码久久毛片| 好爽好湿好硬好大免费视频 | 无码乱人伦一区二区亚洲一| 精品无码一区二区三区爱欲| 人禽交 欧美 网站| 亚洲最大成人av在线天堂网 | 麻豆传传媒久久久爱| 国内精品国产三级国产av| 精品亚洲一区二区三区在线播放| 欧洲精品无码一区二区三区在线播放| 就去干成人网| 女厕偷窥一区二区三区| 亚洲理论在线a中文字幕| 久久av高潮av无码av| 亚洲中文字幕无码一区|