在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RANBP1 Antibody, FITC conjugated

RANBP1 Antibody, FITC conjugated

  • 中文名稱：
    RANBP1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA019308HC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RANBP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RANBP1
  • 別名：
    HTF9A antibody; RAN binding protein 1 antibody; Ran specific GTPase activating protein antibody; Ran-binding protein 1 antibody; Ran-specific GTPase-activating protein antibody; RANBP1 antibody; RANG_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ran-specific GTPase-activating protein (52-111AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L. Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN. Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1. Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP.
  • 基因功能參考文獻：
    1. Sgk1-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells. PMID: 23108393
    2. RANBP1 on 22q11.21 locus might be causally related to the smooth pursuit eye movement abnormality rather than the development of schizophrenia. PMID: 21184585
    3. These data indicate that RANBP1 activity is required for the proper localization of specific factors that regulate microtubule function; loss of this activity contributes to the generation of aneuploidy in a microtubule-dependent manner. PMID: 17940066
    4. RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 dependent. PMID: 19270727
    5. Generation of Ran-GTP from Ran-GDP by importin-beta is activated by Ran-binding protein-1 (RanBP1) that forms a trimeric complex with Ran-GDP and importin-beta. PMID: 19549784

    顯示更多

    收起更多

  • 蛋白家族：
    RANBP1 family
  • 數據庫鏈接：

    HGNC: 9847

    OMIM: 601180

    KEGG: hsa:5902

    STRING: 9606.ENSP00000327583

    UniGene: Hs.24763



主站蜘蛛池模板： 欧美成va视频网站| 亚洲国产精品无码专区成人| 国产成人免费高清直播| 亚洲成av人片在线观看下载| 亚洲熟妇av一区| 欧美群交射精内射颜射潮喷| 亚洲熟女一区二区三区| 深夜福利啪啪片| 在线aⅴ亚洲中文字幕| 激情无码人妻又粗又大中国人| 柠檬福利第一导航在线| 久久久久成人精品无码| 国产区图片区小说区亚洲区 | 久久婷婷丁香七月色综合| 久热中文字幕无码视频| 久久精品人妻中文系列| 理论片午午伦夜理片影院99| 亚洲精品92内射| 国产激情大臿免费视频| 久久久噜噜噜久久熟女| av在线 亚洲 天堂| 成人午夜高潮免费视频| 亚洲高清无在码在线电影不卡 | 色老头精品午夜福利视频| 好男人在线社区www在线影院| 欧美亚洲综合在线一区| 99精品国产在热久久| 久久亚洲一区二区三区舞蹈| 青青草国产精品人人爱| 人妻丰满熟妇av无码区app| 亚洲熟女一区二区三区| 亚洲精品无码一二区a片| 欧美亚洲另类丝袜综合网| 国产精品免费看久久久无码| 亚洲午夜爱爱香蕉片| 国产女人与公拘交在线播放| 国产美女久久精品香蕉| 大屁股熟女一区二区三区| 中国大陆高清aⅴ毛片| 在线涩涩免费观看国产精品| 欧美丰满大爆乳波霸奶水多|