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RAB6B Antibody, Biotin conjugated

  • 中文名稱:
    RAB6B兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA873642LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RAB6B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RAB6B
  • 別名:
    9630015C03 antibody; AI844641 antibody; C330006L04Rik antibody; D9Bwg0185e antibody; OTTHUMP00000216372 antibody; RAB6B antibody; RAB6B member RAS oncogene family antibody; RAB6B_HUMAN antibody; Ras related protein Rab 6B antibody; Ras-related protein Rab-6B antibody; Small GTP binding protein antibody; Small GTPase RAB6B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ras-related protein Rab-6B protein (2-208AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
  • 基因功能參考文獻:
    1. Conformational changes in human neuronal Rab6B between its inactive GDP and active GTP-like state are observed mainly in the switch I and switch II regions, confirming their role as a molecular switch. PMID: 16790928
    2. The brain-specific Rab6B via Bicaudal-D1 is linked to the dynein/dynactin complex, suggesting a regulatory role for Rab6B in the retrograde transport of cargo in neuronal cells. PMID: 17707369
    3. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi. PMID: 18044744
  • 亞細胞定位:
    Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 組織特異性:
    Predominantly expressed in brain.
  • 數據庫鏈接:

    HGNC: 14902

    OMIM: 615852

    KEGG: hsa:51560

    STRING: 9606.ENSP00000285208

    UniGene: Hs.715344



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