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RAB4B Antibody

  • 中文名稱：
    RAB4B兔多克隆抗體
  • 貨號：
    CSB-PA019212LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA019212LA01HU diluted at 1:50 and staining in paraffin-embedded Gastric?cancer?tissue After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • Immunofluorescence staining of Hela cells with CSB-PA019212LA01HU at 1:20, counter-stained with DAPI. The cells were blocked in 10% normal Goat Serum and incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunofluorescence staining of SH-SY5Y cells with CSB-PA019212LA01HU at 1:20, counter-stained with DAPI. The cells were blocked in 10% normal Goat Serum and incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RAB4B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RAB4B
  • 別名：
    1500031G17Rik antibody; FLJ78649 antibody; MGC52123 antibody; OTTMUSP00000026157 antibody; RAB4B antibody; RAB4B; member RAS oncogene family antibody; RAB4B_HUMAN antibody; Ras related GTP binding protein 4b antibody; Ras related protein Rab 4B antibody; Ras-related protein Rab-4B antibody; Small GTP binding protein RAB4B antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Ras-related protein Rab-4B protein (2-213AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，RAB4B Antibody (CSB-PA019212LA01HU)，的標記方式是Non-conjugated。對于RAB4B Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA019212LB01HU RAB4B Antibody, HRP conjugated ELISA
    FITC CSB-PA019212LC01HU RAB4B Antibody, FITC conjugated
    Biotin CSB-PA019212LD01HU RAB4B Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200;IF:1:20-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Protein transport. Probably involved in vesicular traffic. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets.
  • 基因功能參考文獻：
    1. real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B, the read-through long non-coding RNA (lncRNA), RAB4B, PIM2 and TAOK1 share common binding site of a microRNA, miR-24, in their 3'UTRs PMID: 28306719
    2. Interaction between Rab4b and AP1gamma allows the budding of clathrin-coated vesicles for subsequent traffic to recycling endosomes. PMID: 24006255
    3. Data conclude that Rab4b is a new important player in the control of GLUT4 trafficking in adipocyte. PMID: 19590752
  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數據庫鏈接：

    HGNC: 9782

    OMIM: 612945

    KEGG: hsa:53916

    STRING: 9606.ENSP00000469872

    UniGene: Hs.631539



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