在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RAB32 Antibody

  • 中文名稱:
    RAB32兔多克隆抗體
  • 貨號:
    CSB-PA019184GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    RAB32 antibody; RAB32, member RAS oncogene family antibody; RAB32_HUMAN antibody; Ras related protein Rab32 antibody; Ras-related protein Rab-32 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RAB32
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
  • 基因功能參考文獻:
    1. megalin is critical for mitochondrial biology; mitochondrial intracrine signaling is a continuum of the retrograde early endosome-to-Golgi-Rab32 pathway and defects in this pathway may underlie disease processes in many systems. PMID: 29916093
    2. this study provides some compelling evidence showing that Rab32 is an essential host factor required for HCV particle assembly and thus that Rab32 could be a potential therapeutic target to interrupt HCV propagation. PMID: 27852857
    3. Rab32 controls intracellular lipid accumulation through inducing lipolysis via enhancing ATGL expression indirectly. PMID: 26882978
    4. Rab32 may regulate the physiological functions of LRRK2. PMID: 25360523
    5. Rab38 and its close homolog Rab32 bind to Myosin Vc but not to Myosin Va or Myosin Vb. Binding depends on residues in the switch II region of Rab32 and Rab38 and regions of the Myosin Vc coiled-coil tail domain. PMID: 25324551
    6. BLOC-3 is a Rab32 and Rab38 guanine nucleotide exchange factor, with a specific function in the biogenesis of lysosome-related organelles. PMID: 23084991
    7. that Rab38 and Rab32 are the specific factors that direct the ubiquitous machinery to mediate transport from early endosomes to maturing LROs. PMID: 22511774
    8. Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy PMID: 22019778
    9. Rab32 is a dual function protein that participates in both mitochondrial anchoring of PKA and synchronization of mitochondrial fission. PMID: 12186851
    10. RAB32 inactivation may represent a component of the oncogenic pathway of microsatellite-unstable gastrointestinal adenocarcinomas PMID: 16557577
    11. Results suggest that Rab32 facilitates the formation of autophagic vacuoles whose membranes are derived from the ER and regulates the clearance of aggregated proteins by autophagy. PMID: 19593531

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion. Mitochondrion outer membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Melanosome membrane.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 組織特異性:
    Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.
  • 數據庫鏈接:

    HGNC: 9772

    OMIM: 612906

    KEGG: hsa:10981

    STRING: 9606.ENSP00000356465

    UniGene: Hs.287714



主站蜘蛛池模板: 色婷婷久久久swag精品| av中文无码韩国亚洲色偷偷 | 免费无码又爽又刺激毛片| 亚洲性夜色噜噜噜网站2258kk| 人妻夜夜爽天天爽三区丁香花| 5x性社区免费视频播| 欧美人成视频在线视频| 精品国偷自产在线视频99| 人人妻人人澡人人爽秒播| 337p粉嫩日本欧洲亚洲大胆| 久久99热这里只有精品国产| 国内熟妇人妻色无码视频在线| 国产色婷婷亚洲99精品小说| 日日噜噜夜夜狠狠视频| 国产清纯在线一区二区www| 日韩精品无码去免费专区| 中文字幕在线无码一区二区三区| 少妇愉情理伦片高潮日本| 秋霞最新高清无码鲁丝片| 野花社区免费观看在线www| 亚洲综合天堂av网站在线观看| 韩国精品一区二区三区无码视频| 最近中文字幕免费大全在线| 亚洲一区二区三区国产精品无码 | 日韩视频无码免费一区=区三区| 中文无码天天av天天爽| 久久国产精品-国产精品| 女人被躁到高潮免费视频 | 国产精品久久久久久熟妇吹潮软件| 久久天天躁夜夜躁狠狠85麻豆| 婷婷久久香蕉五月综合| 亚洲欧美国产国产一区二区三区 | 久久精品道一区二区三区| 后入到高潮免费观看| 亚洲成a人片在线观看高清| 久久综合少妇11p| 久久青青草免费线频观| 亚洲成a人v影院色老汉影院| 中出あ人妻熟女中文字幕| 日本少妇寂寞少妇aaa| 亚洲婷婷综合色高清在线|